
Mission District Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Mission District Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Embassy Hotel
Downtown San Francisco
Save 100% on your flight
Price was $569, price is now $366 per person
$366
per person
May 14 - May 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
Stay at this hotel in San Francisco. Enjoy valet parking (surcharge), a 24-hour front desk, and daily housekeeping. Popular attractions Lombard Street and Oracle Park are located nearby.

Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $1,620, price is now $939 per person
$939
per person
May 18 - May 25
found 11 hours ago
Roundtrip flight included
Phoenix (PHX) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Oracle Park are located nearby.

The Marker Union Square San Francisco
Union Square
Save 100% on your flight
Price was $1,458, price is now $916 per person
$916
per person
May 18 - May 25
found 11 hours ago
Roundtrip flight included
Phoenix (PHX) to San Francisco (SFO)
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Lombard Street and Oracle Park are located nearby.

Handlery Union Square Hotel
Union Square
Save 100% on your flight
Price was $1,416, price is now $893 per person
$893
per person
May 18 - May 25
found 11 hours ago
Roundtrip flight included
Phoenix (PHX) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.

1 Hotel San Francisco
Downtown San Francisco
Save 100% on your flight
Price was $1,938, price is now $1,246 per person
$1,246
per person
Apr 23 - Apr 27
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Francisco (SFO)
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to Mission District
View all tripsTop Hotel Deals

Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...

Handlery Union Square Hotel
351 Geary St San Francisco CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...

Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
5.36 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...

YOTEL San Francisco
1095 Market St San Francisco CA
2.38 km from Mission District
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...

Hilton San Francisco Financial District
750 Kearny St San Francisco CA
4.13 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...

Hotel Julian
940 Sutter Street San Francisco CA
3.26 km from Mission District
Stay at this hotel in San Francisco. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Pier 39 and Oracle Park are located ...

DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd Berkeley CA
15.11 km from Mission District
Book a stay at this business-friendly hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...

Embassy Hotel
610 Polk St San Francisco CA
2.58 km from Mission District
Stay at this hotel in San Francisco. Enjoy valet parking (surcharge), a 24-hour front desk, and daily housekeeping. Popular attractions Lombard Street and Oracle ...

Hotel Zephyr San Francisco
250 Beach Street San Francisco CA
5.4 km from Mission District
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...

Club Quarters Hotel in San Francisco
424 Clay St San Francisco CA
4.22 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...

Bay Landing San Francisco Airport Hotel
1550 Bayshore Hwy Burlingame CA
18.42 km from Mission District
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

The Marker Union Square San Francisco
501 Geary St San Francisco CA
3.07 km from Mission District
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant ...

Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
2.99 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Don't see what you're looking for?
See all available properties in Mission District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 15 - Wed, Apr 29
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$66 Roundtrip, found 14 hours ago
$66
Roundtrip
found 14 hours ago

Wed, Apr 15 - Wed, Apr 29
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, found 14 hours ago
$117
Roundtrip
found 14 hours ago

Tue, Apr 21 - Wed, Apr 22
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, just found
$117
Roundtrip
just found

Tue, Apr 21 - Wed, Apr 22
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, just found
$117
Roundtrip
just found

Tue, Apr 21 - Wed, Apr 22
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, just found
$117
Roundtrip
just found

