
Mission District Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Mission District Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

SF Plaza Hotel
Union Square
Save 100% on your flight
Price was $490, price is now $330 per person
$330
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and an airport shuttle (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

Bay Landing San Francisco Airport Hotel
Ingold - Milldale
Save 100% on your flight
Price was $594, price is now $342 per person
$342
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bayfront Park and Millbrae Square Shopping Center are located nearby.

Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $781, price is now $471 per person
$471
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

Holiday Inn Express and Suites Fisherman's Wharf by IHG
Fisherman's Wharf
Save 100% on your flight
Price was $550, price is now $366 per person
$366
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

Nob Hill Hotel
Downtown San Francisco
Save 100% on your flight
Price was $681, price is now $464 per person
$464
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

Suites At Fishermans Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $772, price is now $528 per person
$528
per person
Jan 16 - Jan 20
just found
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
Stay at this hotel in San Francisco. Enjoy free WiFi, a rooftop terrace, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.
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Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
5.3 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...

Fairmont San Francisco
950 Mason Street Atop Nob Hill San Francisco CA
3.72 km from Mission District
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...

Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...

DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd Berkeley CA
15.18 km from Mission District
Book a stay at this business-friendly hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...

Hyatt Place San Francisco Downtown
701 3rd St San Francisco CA
3.04 km from Mission District
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the breakfast and the helpful staff in ...

Hilton San Francisco Financial District
750 Kearny St San Francisco CA
4.11 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...

Club Quarters Hotel in San Francisco
424 Clay St San Francisco CA
4.2 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...

Hyatt Regency San Francisco
5 Embarcadero Center San Francisco CA
4.22 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...

Hyatt Centric Fisherman's Wharf San Francisco
555 N Point St San Francisco CA
5.23 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...

Chancellor Hotel on Union Square
433 Powell St San Francisco CA
3.35 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...

Hotel Zoe Fisherman's Wharf
425 North Point San Francisco CA
5.26 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and ...

Mayflower Hotel
975 Bush St San Francisco CA
3.36 km from Mission District
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Pier 39 and Golden Gate Bridge are located ...

Handlery Union Square Hotel
351 Geary St San Francisco CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Don't see what you're looking for?
See all available properties in Mission District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 13 - Wed, Jan 14
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$68 Roundtrip, found 16 hours ago
$68
Roundtrip
found 16 hours ago

Tue, Jan 13 - Tue, Jan 20
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, found 16 hours ago
$117
Roundtrip
found 16 hours ago

Sat, Jan 17 - Tue, Jan 20
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$117 Roundtrip, found 16 hours ago
$117
Roundtrip
found 16 hours ago

Fri, Jan 16 - Tue, Jan 20
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$131 Roundtrip, found 16 hours ago
$131
Roundtrip
found 16 hours ago

Thu, Jan 15 - Fri, Jan 16
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$170 Roundtrip, found 16 hours ago
$170
Roundtrip
found 16 hours ago

