Mission District Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

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Mission District Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Fitzgerald Hotel

Fitzgerald Hotel

3 out of 5
Union Square
Save 100% on your flight
Price was $511, price is now $259 per person
$259
per person
Oct 28 - Nov 1
found 20 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Save 100% on your flight
Price was $576, price is now $330 per person
$330
per person
Oct 28 - Nov 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bayfront Park and Millbrae Square Shopping Center are located nearby.

Argonaut Hotel

Argonaut Hotel

4.5 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $1,110, price is now $665 per person
$665
per person
Oct 29 - Nov 3
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Francisco (SFO)
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby.

Nob Hill Hotel

Nob Hill Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $697, price is now $419 per person
$419
per person
Oct 28 - Nov 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
Stay at this 4-star hotel in San Francisco. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Oracle Park are located nearby.

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $794, price is now $487 per person
$487
per person
Oct 28 - Nov 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby.

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $923, price is now $566 per person
$566
per person
Oct 25 - Oct 30
found 1 day ago
Roundtrip non-stop flight included
Chicago (ORD) to San Francisco (SFO)
Stay at this 3-star hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.

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Top Hotel Deals

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
5.3 km from Mission District
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
4.22 km from Mission District
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
4.11 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
19.41 km from Mission District
Stay at this 3.5-star business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the ...
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
4.2 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St, San Francisco, CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St, San Francisco, CA
5.23 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill, San Francisco, CA
3.72 km from Mission District
Stay at this 5-star luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the property ...
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
200 Marina Blvd, Berkeley, CA
15.18 km from Mission District
Stay at this 4-star eco-certified hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St, San Francisco, CA
3.35 km from Mission District
Stay at this 3.5-star hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean ...
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy, Burlingame, CA
18.41 km from Mission District
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4 out of 5
345 Stockton St, San Francisco, CA
3.43 km from Mission District
Book a stay at this eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4 out of 5
1300 Columbus Avenue, San Francisco, CA
5.26 km from Mission District
Stay at this 4-star family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St, San Francisco, CA
2.92 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
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See all available properties in Mission District
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Tue, Oct 14 - Wed, Oct 15
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$76 Roundtrip, found 5 days ago
$76
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Oct 14 from Los Angeles Intl. to San Francisco Intl., returning Wed, Oct 15, priced at $76 found 5 days ago
American Airlines
Wed, Nov 19 - Tue, Dec 2
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 19 from Los Angeles Intl. to San Francisco Intl., returning Tue, Dec 2, priced at $97 found 1 day ago
Delta
Wed, Nov 19 - Tue, Dec 2
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Nov 19 from Los Angeles Intl. to San Francisco Intl., returning Tue, Dec 2, priced at $97 found 1 day ago
United
Wed, Nov 19 - Tue, Dec 2
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select United flight, departing Wed, Nov 19 from Los Angeles Intl. to San Francisco Intl., returning Tue, Dec 2, priced at $97 found 1 day ago
Alaska Airlines
Wed, Nov 19 - Tue, Dec 2
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$107 Roundtrip, found 1 day ago
$107
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Nov 19 from Los Angeles Intl. to San Francisco Intl., returning Tue, Dec 2, priced at $107 found 1 day ago