Mission District Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Mission District Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel
per person
Jul 17 - Jul 21
found 13 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions GoKart Racer and Bayfront Park are located nearby.
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
per person
Jul 17 - Jul 21
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Lombard Street are located nearby.
The Andrews Hotel
Union Square
per person
Jul 17 - Jul 21
found 13 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Stay at this 3-star hotel in San Francisco. Enjoy free WiFi, room service, and a 24-hour front desk. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.
Hotel Zephyr San Francisco
Fisherman's Wharf
per person
Jul 17 - Jul 21
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Stay at this 4-star boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Lombard Street are located nearby.
The Marker Union Square San Francisco
Union Square
per person
Jul 17 - Jul 21
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Lombard Street and Oracle Park are located nearby.
Handlery Union Square Hotel
Union Square
per person
Jul 17 - Jul 21
found 13 hours ago
Roundtrip flight included
Detroit (DTW) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Lombard Street and Oracle Park are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to Mission District
View all tripsTop Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave, San Francisco, CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St, San Francisco, CA
5.3 km from Mission District
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Handlery Union Square Hotel
351 Geary St, San Francisco, CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Club Quarters Hotel in San Francisco
424 Clay St, San Francisco, CA
4.2 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Chancellor Hotel on Union Square
433 Powell St, San Francisco, CA
3.35 km from Mission District
Stay at this 3.5-star hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean ...
Hyatt Regency San Francisco
5 Embarcadero Center, San Francisco, CA
4.22 km from Mission District
Book a stay at this eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hilton San Francisco Financial District
750 Kearny St, San Francisco, CA
4.11 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
The Andrews Hotel
624 Post St, San Francisco, CA
3.21 km from Mission District
Stay at this 3-star hotel in San Francisco. Enjoy free WiFi, room service, and a 24-hour front desk. Our guests praise the restaurant and the helpful staff in ...
Hilton San Francisco Union Square
333 O'Farrell St., San Francisco, CA
3.04 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Beacon Grand, A Union Square Hotel
450 Powell Street, San Francisco, CA
3.38 km from Mission District
Stay at this 4-star historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
King George Hotel
334 Mason Street, San Francisco, CA
3.11 km from Mission District
Stay at this 3-star business-friendly hotel in San Francisco. Enjoy valet parking (surcharge), a 24-hour front desk, and daily housekeeping. Our guests praise ...
Marriott Vacation Club®, San Francisco
2620 Jones St, San Francisco, CA
5.13 km from Mission District
Stay at this 3-star eco-certified hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful ...
DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd, Berkeley, CA
15.18 km from Mission District
Stay at this 4-star business-friendly hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
Don't see what you're looking for?
See all available properties in Mission District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Fri, Jun 6 - Sat, Jun 7
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$124 Roundtrip, found 1 day ago
$124
Roundtrip
found 1 day ago
Tue, Jul 29 - Wed, Aug 6
ORD
O'Hare Intl.
SFO
San Francisco Intl.
$197 Roundtrip, found 3 days ago
$197
Roundtrip
found 3 days ago
Thu, May 29 - Fri, May 30
JFK
John F. Kennedy Intl.
SFO
San Francisco Intl.
$217 Roundtrip, found 5 days ago
$217
Roundtrip
found 5 days ago
Tue, Sep 2 - Tue, Sep 9
BOS
Logan Intl.
SFO
San Francisco Intl.
$237 Roundtrip, found 2 days ago
$237
Roundtrip
found 2 days ago
Best points of interest in San Francisco
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More Types of Hotels
- Hotels with WiFi in Mission District
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- Hotel with wifi in Mission District
- Hotels with Bars in Mission District
- Beach Hotels in Mission District
- Family Hotels in Mission District
- Hotels with Balconies in Mission District
- Cheap Hotels in Mission District
- Hotels with Complimentary Breakfast in Mission District
- Resorts & Hotels with Spas in Mission District
- Pet-friendly Hotels in Mission District
- Hotels with Air Conditioning in Mission District
- Luxury Hotels in Mission District
- Adults Only Resorts & Hotels in Mission District
- Hotel with a Concierge in Mission District
- Hotels with Hot Tubs in Mission District
- Hotels with smoking rooms in Mission District