
Mission District Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Mission District Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Bay Landing San Francisco Airport Hotel
Save 100% on your flight  
Price was $622, price is now $394 per person
$394
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bayfront Park and Millbrae Square Shopping Center are located nearby. 

Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight  
Price was $620, price is now $425 per person
$425
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby. 

Holiday Inn Express and Suites Fisherman's Wharf by IHG
Fisherman's Wharf
Price was $562, price is now $398 per person
$398
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby. 

Argonaut Hotel
Fisherman's Wharf
Save 100% on your flight  
Price was $741, price is now $533 per person
$533
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby. 

The Marker Union Square San Francisco
Union Square
Price was $635, price is now $473 per person
$473
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby. 

Nob Hill Hotel
Downtown San Francisco
Price was $550, price is now $412 per person
$412
per person
Dec 11 - Dec 15
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to San Francisco (SFO)
Stay at this 4-star hotel in San Francisco. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Oracle Park are located nearby. 
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See all available trips from Columbus to Mission District
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Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave, San Francisco, CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...

Hotel Riu Plaza Fisherman's Wharf
2500 Mason St, San Francisco, CA
5.3 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...

Hyatt Regency San Francisco
5 Embarcadero Center, San Francisco, CA
4.22 km from Mission District
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...

DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd, Berkeley, CA
15.18 km from Mission District
Stay at this 4-star eco-certified hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...

Crowne Plaza San Francisco Airport by IHG
1177 Airport Blvd, Burlingame, CA
19.41 km from Mission District
Stay at this 3.5-star business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the ...

Fairmont San Francisco
950 Mason Street Atop Nob Hill, San Francisco, CA
3.72 km from Mission District
Stay at this 5-star luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the property ...

Hilton San Francisco Financial District
750 Kearny St, San Francisco, CA
4.11 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...

Handlery Union Square Hotel
351 Geary St, San Francisco, CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...

Club Quarters Hotel in San Francisco
424 Clay St, San Francisco, CA
4.2 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...

Hyatt Centric Fisherman's Wharf San Francisco
555 N Point St, San Francisco, CA
5.23 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...

Claremont Resort & Club
41 Tunnel Road, Berkeley, CA
18.93 km from Mission District
Stay at this 5-star luxury hotel in Berkeley. Enjoy 3 outdoor pools, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the property ...

Chancellor Hotel on Union Square
433 Powell St, San Francisco, CA
3.35 km from Mission District
Stay at this 3.5-star business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful ...

Comfort Inn by the Bay
2775 Van Ness Ave, San Francisco, CA
4.72 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the ...
Don't see what you're looking for?
See all available properties in Mission District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 19 - Wed, Dec 3
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$64 Roundtrip, found 6 days ago
$64
Roundtrip
found 6 days ago

Wed, Nov 19 - Wed, Dec 3
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$93 Roundtrip, found 6 days ago
$93
Roundtrip
found 6 days ago

Tue, Jan 20 - Tue, Feb 10
ORD
O'Hare Intl.
SFO
San Francisco Intl.
$157 Roundtrip, found 6 days ago
$157
Roundtrip
found 6 days ago

Tue, Jan 20 - Tue, Feb 10
ORD
O'Hare Intl.
SFO
San Francisco Intl.
$211 Roundtrip, found 6 days ago
$211
Roundtrip
found 6 days ago

Sun, Feb 15 - Sat, Feb 21
EWR
Newark Liberty Intl. Airport
SFO
San Francisco Intl.
$217 Roundtrip, found 2 days ago
$217
Roundtrip
found 2 days ago

