Mission District Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

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Mission District Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Save 100% on your flight
per person
Oct 1 - Oct 7
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bayfront Park and Millbrae Square Shopping Center are located nearby.

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
per person
Oct 1 - Oct 7
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby.

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
per person
Oct 1 - Oct 7
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby.

The Andrews Hotel

The Andrews Hotel

4 out of 5
Union Square
Save 100% on your flight
per person
Oct 1 - Oct 7
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and room service. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
per person
Oct 1 - Oct 7
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this 4-star family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Pier 39 and Alcatraz Island are located nearby.

Graduate by Hilton Palo Alto

Graduate by Hilton Palo Alto

4 out of 5
University South
Save 100% on your flight
per person
Oct 2 - Oct 8
found 23 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this 4-star hotel in Palo Alto. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Shoreline Amphitheatre and Stanford Theatre are located nearby.

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Top Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
5.3 km from Mission District
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
4.11 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
19.41 km from Mission District
Stay at this 3.5-star business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the ...
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
4.22 km from Mission District
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street, San Francisco, CA
3.64 km from Mission District
Stay at this 4-star luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
Soma House

Soma House

3.5 out of 5
121 7th Street, San Francisco, CA
2.25 km from Mission District
Stay at this 3.5-star hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms ...
Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 out of 5
222 Mason St, San Francisco, CA
3 km from Mission District
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, a nightclub, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4 out of 5
1300 Columbus Avenue, San Francisco, CA
5.26 km from Mission District
Stay at this 4-star family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Kimpton Alton Fisherman's Wharf by IHG

Kimpton Alton Fisherman's Wharf by IHG

4.5 out of 5
2700 JONES STREET, San Francisco, CA
5.26 km from Mission District
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St, San Francisco, CA
3.18 km from Mission District
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
425 North Point, San Francisco, CA
5.26 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and ...
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St, San Francisco, CA
3.35 km from Mission District
Stay at this 3.5-star hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean ...
Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG

4 out of 5
405 Taylor St, San Francisco, CA
3.03 km from Mission District
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and a 24-hour front desk. Our guests praise ...
Hotel Julian

Hotel Julian

3 out of 5
940 Sutter Street, San Francisco, CA
3.26 km from Mission District
Stay at this 3-star hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Popular attractions Pier 39 and Oracle Park are located ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Aug 6 - Tue, Aug 12
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$70 Roundtrip, found 4 days ago
$70
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Aug 6 from Los Angeles Intl. to San Francisco Intl., returning Tue, Aug 12, priced at $70 found 4 days ago
United
Thu, Nov 27 - Sun, Dec 7
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$107 Roundtrip, found 5 days ago
$107
Roundtrip
found 5 days ago
Select United flight, departing Thu, Nov 27 from Los Angeles Intl. to San Francisco Intl., returning Sun, Dec 7, priced at $107 found 5 days ago
Alaska Airlines
Tue, Nov 25 - Sat, Dec 6
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$134 Roundtrip, found 5 days ago
$134
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Tue, Nov 25 from Los Angeles Intl. to San Francisco Intl., returning Sat, Dec 6, priced at $134 found 5 days ago
Hawaiian Airlines
Mon, Dec 1 - Wed, Dec 10
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$150 Roundtrip, found 6 days ago
$150
Roundtrip
found 6 days ago
Select Hawaiian Airlines flight, departing Mon, Dec 1 from Los Angeles Intl. to San Francisco Intl., returning Wed, Dec 10, priced at $150 found 6 days ago
Delta
Sat, Sep 27 - Mon, Sep 29
JFK
John F. Kennedy Intl.
SFO
San Francisco Intl.
$181 Roundtrip, found 6 days ago
$181
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Sep 27 from John F. Kennedy Intl. to San Francisco Intl., returning Mon, Sep 29, priced at $181 found 6 days ago