Mission District Vacation Packages for 2026

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

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Mission District Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Cathedral Hill Hotel

Cathedral Hill Hotel

2 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $669, price is now $439 per person
$439
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this motel in San Francisco. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Ingold - Milldale
Save 100% on your flight
Price was $983, price is now $535 per person
$535
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bayfront Park and Millbrae Square Shopping Center are located nearby.

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $1,304, price is now $730 per person
$730
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $2,890, price is now $1,781 per person
$1,781
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

SF Central Hotel

SF Central Hotel

2 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $830, price is now $543 per person
$543
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Stay at this hotel in San Francisco. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions Pier 39 and Golden Gate Park are located nearby.

Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4 out of 5
Union Square
Save 100% on your flight
Price was $1,446, price is now $955 per person
$955
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
Book a stay at this historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Pier 39 and Golden Gate Bridge are located nearby.

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Top Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
3.43 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
5.36 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
4.13 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

3 out of 5
701 3rd St San Francisco CA
3.04 km from Mission District
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the breakfast and the helpful staff in ...
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
3.17 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
4.22 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
4.3 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
2.38 km from Mission District
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
3.73 km from Mission District
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
200 Marina Blvd Berkeley CA
15.11 km from Mission District
Book a stay at this business-friendly hotel in Berkeley. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
3.34 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St San Francisco CA
3.43 km from Mission District
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
2.99 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
18.42 km from Mission District
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St San Francisco CA
5.19 km from Mission District
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
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See all available properties in Mission District
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Mon, Feb 9 - Tue, Feb 10
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$123 Roundtrip, found 5 days ago
$123
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Mon, Feb 9 from Los Angeles Intl. to San Francisco Intl., returning Tue, Feb 10, priced at $123 found 5 days ago
Southwest Airlines
Thu, Feb 12 - Sat, Feb 21
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$162 Roundtrip, found 14 hours ago
$162
Roundtrip
found 14 hours ago
Select Southwest Airlines flight, departing Thu, Feb 12 from Los Angeles Intl. to San Francisco Intl., returning Sat, Feb 21, priced at $162 found 14 hours ago
American Airlines
Thu, Feb 12 - Sat, Feb 21
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$165 Roundtrip, found 14 hours ago
$165
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Feb 12 from Los Angeles Intl. to San Francisco Intl., returning Sat, Feb 21, priced at $165 found 14 hours ago
Delta
Thu, Feb 12 - Sat, Feb 21
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$168 Roundtrip, found 14 hours ago
$168
Roundtrip
found 14 hours ago
Select Delta flight, departing Thu, Feb 12 from Los Angeles Intl. to San Francisco Intl., returning Sat, Feb 21, priced at $168 found 14 hours ago
United
Thu, Feb 12 - Sat, Feb 21
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$168 Roundtrip, found 14 hours ago
$168
Roundtrip
found 14 hours ago
Select United flight, departing Thu, Feb 12 from Los Angeles Intl. to San Francisco Intl., returning Sat, Feb 21, priced at $168 found 14 hours ago