Downtown Santiago Vacation Packages for 2026

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Mercure Santiago Centro

Mercure Santiago Centro

4 out of 5
Av. Libertador Bernardo O Higgins, 632 Santiago Region Metropolitana
1.54 km from Downtown Santiago
Book a stay at this business-friendly hotel in Santiago. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in ...
Hotel Plaza San Francisco

Hotel Plaza San Francisco

4 out of 5
Alameda 816 Santiago Region Metropolitana
1.28 km from Downtown Santiago
Book a stay at this spa hotel in Santiago. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the bar in our reviews. ...
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
1.48 km from Downtown Santiago
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Park Plaza Apart Hotel

Park Plaza Apart Hotel

3 out of 5
Av. Huerfanos 545 Santiago Region Metropolitana
1.91 km from Downtown Santiago
Book a stay at this business-friendly aparthotel in Santiago. Enjoy free WiFi, free parking, and a health club. Our guests praise the helpful staff in our reviews. ...
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
2.3 km from Downtown Santiago
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
Hotel Cumbres Lastarria

Hotel Cumbres Lastarria

4 out of 5
Jose Victorino Lastarria 299 Santiago Region Metropolitana
2.23 km from Downtown Santiago
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hotel HW Libertad

Hotel HW Libertad

3.5 out of 5
22 Libertad Santiago Región Metropolitana
1.64 km from Downtown Santiago
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Movistar Arena and Plaza de Armas are located ...
Nest Paris-Londres

Nest Paris-Londres

3 out of 5
50 Londres Santiago
1.21 km from Downtown Santiago
Stay at this apartment in Santiago. Enjoy free WiFi, a rooftop terrace, and concierge services. Popular attractions Plaza de Armas and Movistar Arena are located ...
Hotel Magnolia

Hotel Magnolia

4 out of 5
Calle Huérfanos 539 Santiago Región Metropolitana
1.93 km from Downtown Santiago
Book a stay at this spa hotel in Santiago. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Luciano K Hotel

Luciano K Hotel

4.5 out of 5
Merced, 84 Santiago Región Metropolitana
2.59 km from Downtown Santiago
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the bar in our reviews. ...
Hotel Fundador

Hotel Fundador

4 out of 5
Serrano 34 Santiago Region Metropolitana
1.15 km from Downtown Santiago
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the helpful staff and the property ...
Debaines Hotel Santiago

Debaines Hotel Santiago

3.5 out of 5
Agustinas 720 Santiago
1.66 km from Downtown Santiago
Stay at this hotel in Santiago. Enjoy free breakfast, 24-hour room service, and onsite spa services. Popular attractions Plaza de Armas and Movistar Arena are ...
Hotel Gran Palace

Hotel Gran Palace

4 out of 5
Huerfanos 1178 Santiago
1.49 km from Downtown Santiago
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza de Armas and Movistar Arena are located nearby.
Novapark

Novapark

3 out of 5
Presidente Juan Antonio Rios 59 Santiago Región Metropolitana de Santiago
1.35 km from Downtown Santiago
Stay at this hotel in Santiago. Enjoy free WiFi, a 24-hour front desk, and a business center. Our guests praise the helpful staff and the clean rooms in our ...
Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

4.5 out of 5
Coronel Santiago Bueras 188 Santiago Region Metropolitana
2.42 km from Downtown Santiago
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
Don't see what you're looking for?
See all available properties in Downtown Santiago
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Tue, Nov 3 - Tue, Nov 17
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$561 Roundtrip, found 1 day ago
$561
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Tue, Nov 3 from Miami Intl. to Arturo Merino Benitez, returning Tue, Nov 17, priced at $561 found 1 day ago
Delta
Tue, Sep 15 - Tue, Sep 22
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$632 Roundtrip, found 3 days ago
$632
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Sep 15 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, Sep 22, priced at $632 found 3 days ago
LATAM Airlines Group
Tue, Sep 15 - Tue, Sep 22
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$642 Roundtrip, found 3 days ago
$642
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Sep 15 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, Sep 22, priced at $642 found 3 days ago
American Airlines
Tue, Sep 15 - Tue, Sep 22
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$646 Roundtrip, found 3 days ago
$646
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Sep 15 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, Sep 22, priced at $646 found 3 days ago
Copa
Tue, Nov 3 - Tue, Nov 17
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$719 Roundtrip, found 1 day ago
$719
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Nov 3 from Miami Intl. to Arturo Merino Benitez, returning Tue, Nov 17, priced at $719 found 1 day ago