South America Vacations & Trips

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Top destinations in South America

A historic building with ornate architecture and a large entrance.

São Paulo

São Paulo
A panoramic view of Rio de Janeiro at sunset, featuring the Christ the Redeemer statue, Sugarloaf Mountain, Guanabara Bay, and the cityscape with cable cars.

Rio de Janeiro

Rio de Janeiro
A narrow street lined with colorful buildings, featuring balconies and potted plants.

Cartagena

Cartagena
A plaza with a large building featuring a dome and spires, surrounded by trees and people.

Medellín

Medellín
A village with traditional architecture, surrounded by lush green mountains and a prominent church.

Bogotá

Bogotá
A cityscape with historic buildings, a prominent clock tower, and modern skyscrapers under a clear blue sky.

Buenos Aires

Buenos Aires
A stone bridge, a fountain, and a restaurant with a red awning.

Gramado

Gramado
A multi-tiered waterfall surrounded by lush greenery.

Foz do Iguaçu

Foz do Iguaçu

South America Hotel Deals

Rochester Classic

Rochester Classic

Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

25 De Mayo 630 Buenos Aires Capital Federal
Concorde Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular South America attractions

A beach with a road running parallel to it, palm trees, and buildings in the background.

Copacabana Beach

9.0/10 (5,319 reviews)
Nothing says vacation like spending a lazy day at Copacabana Beach, a popular beach in Rio de Janeiro. Amble around this romantic area's seaside and enjoy its top-notch restaurants.
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A city street with modern buildings, a bridge, and a clear sky.

Paulista Avenue

9.0/10 (2,555 reviews)
You can search for that perfect souvenir with a trip to Paulista Avenue, a favorite shopping spot in São Paulo. While you're here, you can savor the top-notch restaurants.
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An aerial view of a city with a large racetrack surrounded by residential and commercial buildings.

Interlagos Race Track

8.4/10 (385 reviews)
Interlagos Race Track is one of the more well-known attractions to visit during your trip to São Paulo. Experience the art scene and museums in this culturally rich area.
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