Vacation Packages to Panama for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
147.07 km from city center
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
149.41 km from city center
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
137.86 km from city center
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
164.19 km from city center
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
146.51 km from city center
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
148.72 km from city center
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
147.16 km from city center
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
147.27 km from city center
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 out of 5
Via Veneto, El Cangrejo Bellavista, Panama City, Panama
146.43 km from city center
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
146.44 km from city center
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
Don't see what you're looking for?
See all available properties in Panama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Aug 1 - Mon, Aug 4
MIA
Miami Intl.
PTY
Tocumen Intl.
$276 Roundtrip, found 2 days ago
$276
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Aug 1 from Miami Intl. to Tocumen Intl., returning Mon, Aug 4, priced at $276 found 2 days ago
Delta
Tue, Jul 22 - Sun, Jul 27
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$407 Roundtrip, found 1 day ago
$407
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 22 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sun, Jul 27, priced at $407 found 1 day ago
avianca
Thu, Jul 17 - Fri, Jul 18
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$592 Roundtrip, found 3 days ago
$592
Roundtrip
found 3 days ago
Select avianca flight, departing Thu, Jul 17 from John F. Kennedy Intl. to Tocumen Intl., returning Fri, Jul 18, priced at $592 found 3 days ago
United
Wed, Oct 15 - Sun, Oct 19
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$599 Roundtrip, found 1 day ago
$599
Roundtrip
found 1 day ago
Select United flight, departing Wed, Oct 15 from Newark Liberty Intl. Airport to Tocumen Intl., returning Sun, Oct 19, priced at $599 found 1 day ago