Vacation Packages to Panama for 2025

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FlightsFlightsHotelsHotels

Panama City

Panama City

Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
147.07 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
164.19 km from city center
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
147.43 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
146.49 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
149.41 km from city center
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
147.27 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
137.86 km from city center
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
146.97 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
143.4 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
146.67 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Feb 10 - Thu, Feb 19
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$332 Roundtrip, found 13 hours ago
$332
Roundtrip
found 13 hours ago
Select United flight, departing Tue, Feb 10 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Thu, Feb 19, priced at $332 found 13 hours ago
Copa
Thu, Feb 12 - Fri, Feb 20
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$341 Roundtrip, found 11 hours ago
$341
Roundtrip
found 11 hours ago
Select Copa flight, departing Thu, Feb 12 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Fri, Feb 20, priced at $341 found 11 hours ago
avianca
Thu, Feb 12 - Fri, Feb 20
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$426 Roundtrip, found 11 hours ago
$426
Roundtrip
found 11 hours ago
Select avianca flight, departing Thu, Feb 12 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Fri, Feb 20, priced at $426 found 11 hours ago
Delta
Sun, Mar 22 - Tue, Apr 7
LAX
Los Angeles Intl.
PTY
Tocumen Intl.
$613 Roundtrip, found 6 days ago
$613
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Mar 22 from Los Angeles Intl. to Tocumen Intl., returning Tue, Apr 7, priced at $613 found 6 days ago
American Airlines
Tue, Jan 13 - Tue, Jan 20
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$624 Roundtrip, found 21 hours ago
$624
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Tue, Jan 13 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Jan 20, priced at $624 found 21 hours ago