Vacation Packages to Panama for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Search vacation deals in Panama's top destinations
Panama City
Top Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
147.07 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
164.19 km from city center
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
147.27 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
146.49 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
147.32 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
147.43 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
143.4 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Principe Hotel and Suites
Via Argentina Panama City Panama
146.97 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Grand Decameron Panama, A Trademark All Inclusive Resort
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
74.56 km from city center
Book a stay at this beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón Beach ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Jan 28 - Sun, Feb 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$375 Roundtrip, found 13 hours ago
$375
Roundtrip
found 13 hours ago
Wed, Jan 28 - Sun, Feb 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$409 Roundtrip, found 13 hours ago
$409
Roundtrip
found 13 hours ago
Wed, Jan 28 - Sun, Feb 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$424 Roundtrip, found 13 hours ago
$424
Roundtrip
found 13 hours ago
Mon, Feb 23 - Wed, Mar 11
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$429 Roundtrip, found 4 days ago
$429
Roundtrip
found 4 days ago
Wed, Jan 28 - Sun, Feb 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$513 Roundtrip, found 13 hours ago
$513
Roundtrip
found 13 hours ago