
Vacation Packages to Panama for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

4.0-star property
Hotel Casa Panamá
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $784, price is now $638 per person
$638
per person
found 1 day ago
Stay at this 4-star hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

4.0-star property
Central Hotel Panama Casco Viejo
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Save 100% on your flight
Price was $1,602, price is now $966 per person
$966
per person
found 1 day ago
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

5.0-star property
Hotel Riu Plaza Panama
Bella Vista
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $1,017, price is now $744 per person
$744
per person
found 1 day ago
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

5.0-star property
Bristol Panama, a Registry Collection Hotel
Bella Vista
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
American Airlines • Non-stop • Coach
Price was $1,293, price is now $962 per person
$962
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

4.0-star property
Dreams Playa Bonita Panama - All Inclusive
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
American Airlines • Non-stop • Coach
Price was $1,662, price is now $1,245 per person
$1,245
per person
found 4 hours ago
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

4.0-star property
Las Americas Golden Tower Panama
San Francisco
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $1,042, price is now $823 per person
$823
per person
found 1 day ago
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

4.0-star property
Casa Mallet by Wynwood House
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $1,099, price is now $870 per person
$870
per person
found 1 day ago
Stay at this 4-star apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

3.5-star property
MARINN PLACE Financial District
Bella Vista
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $1,051, price is now $835 per person
$835
per person
found 2 hours ago
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

4.0-star property
La Concordia Boutique Hotel
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $1,201, price is now $963 per person
$963
per person
found 1 day ago
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

3.0-star property
Centriqo by Wynwood house
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $994, price is now $799 per person
$799
per person
found 1 day ago
Stay at this 3-star apartment in Veracruz. Enjoy free WiFi, air conditioning, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

4.0-star property
Casa Contemporanea by Wynwood House
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $933, price is now $765 per person
$765
per person
found 1 hour ago
Stay at this 4-star apartment in Panama City. Enjoy free WiFi, satellite TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

3.5-star property
Casa La Costa By Wynwood House
Casco Viejo
Nov 3 - Nov 8
5 night stay
Kansas City (MCI) to Panama City (PTY)
Delta • Non-stop • Coach
Panama City (PTY) to Kansas City (MCI)
United • Non-stop • Coach
Price was $898, price is now $745 per person
$745
per person
found 2 hours ago
Stay at this 3.5-star apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Search vacation deals in Panama's top destinations

Panama City
Top Hotel Deals

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
147.07 km from city center
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz, Veracruz, Panama
137.86 km from city center
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
146.44 km from city center
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
164.19 km from city center
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
149.41 km from city center
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

The Westin Playa Bonita Panama
Km 6 Road to Veracruz, Veracruz, Panama
138.41 km from city center
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

Megapolis Hotel Panamá
Avenida Balboa, Panama City
147.27 km from city center
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Principe Hotel and Suites
Via Argentina, Panama City, Panama
146.97 km from city center
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 23 - Tue, Oct 21
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$209 Roundtrip, found 4 days ago
$209
Roundtrip
found 4 days ago

Tue, Sep 23 - Tue, Oct 21
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$230 Roundtrip, found 4 days ago
$230
Roundtrip
found 4 days ago

Tue, Sep 23 - Wed, Oct 1
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$391 Roundtrip, found 4 days ago
$391
Roundtrip
found 4 days ago

Sun, Nov 9 - Sat, Nov 15
MIA
Miami Intl.
PTY
Tocumen Intl.
$409 Roundtrip, found 5 days ago
$409
Roundtrip
found 5 days ago

Sun, Nov 9 - Sat, Nov 15
MIA
Miami Intl.
PTY
Tocumen Intl.
$488 Roundtrip, found 5 days ago
$488
Roundtrip
found 5 days ago