Cheap 2025 Uptown Hotels
Choose from 1419 Uptown Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.8 km from Uptown
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.68 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Drury Inn & Suites St. Louis Union Station
201 S 20th St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
19.48 km from Uptown
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
River City Casino & Hotel
777 River City Casino Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
28.19 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
30.11 km from Uptown
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.93 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.47 km from Uptown
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Moonrise Hotel
6177 Delmar Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
26.77 km from Uptown
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
21C Museum Hotel St Louis
1528 Locust street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
18.79 km from Uptown
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Casino Queen Hotel
200 Front Street, East St. Louis, IL
Free Cancellation
Reserve now, pay when you stay
16.66 km from Uptown
Stay at this 3-star business-friendly hotel in East St. Louis. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean ...
Live by Loews - St.Louis
799 Clark ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
18.26 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Marriott St. Louis Grand
800 Washington Ave, St. Louis, MO
17.9 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
Hilton St. Louis at the Ballpark
1 S Broadway, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.98 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the clean rooms in our ...
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
19.27 km from Uptown
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
Hilton Pennywell St. Louis at the Arch
400 Olive St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
17.7 km from Uptown
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Uptown, Collinsville Hotel Guide
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More Uptown Hotel Deals for Seniors and Members
- Drury Plaza Hotel St. Louis at the Arch
- Hyatt Regency St. Louis at The Arch
- Drury Inn & Suites St. Louis Union Station
- River City Casino & Hotel
- Clayton Plaza Hotel & Extended Stay
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Moonrise Hotel
- 21C Museum Hotel St Louis
- Casino Queen Hotel