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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with a fitness center and a steam room

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Lobby
Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace
Indoor pool

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Room options

Available filters for rooms
Showing 15 of 15 rooms

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | 1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Shower/tub combination
Bathrobes
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Room, 1 King Bed, Corner

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Shower/tub combination
Bathrobes
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the neighborhood

Map
1528 Locust street, St. Louis, MO, 63103

What's nearby

  • St. Louis Union Station - 6 min walk - 0.4 miles
  • Enterprise Center - 6 min walk - 0.4 miles
  • City Museum - 6 min walk - 0.4 miles
  • Busch Stadium - 14 min walk - 0.8 miles
  • Gateway Arch - 2 min drive - 1.1 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel near City Museum
A short walk from St. Louis Union Station and Enterprise Center, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services, and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business center, guests can connect to free in-room WiFi.
You'll also enjoy the following perks during your stay:
  • An indoor pool
  • Cooked-to-order breakfast (surcharge), valet parking (surcharge), and an elevator
  • A billiards/pool table, a vending machine, and smoke-free premises
  • Luggage storage, ATM/banking services, and meeting rooms
  • Guest reviews speak highly of the dining options, pool, and helpful staff
Room features
All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks like free WiFi and desk chairs. Guest reviews highly rate the clean rooms at the property.
More amenities include:
  • Free toiletries and hair dryers
  • Flat-screen TVs with premium channels
  • Wardrobes/closets, heating, and daily housekeeping

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Does 21C Museum Hotel St Louis have a pool?

Yes, this property has an indoor pool.

Is 21C Museum Hotel St Louis pet-friendly?

Yes, dogs are allowed at this property. There's a fee of USD 100 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21C Museum Hotel St Louis ?

Valet parking is available for USD 50 per day.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM. Late check-in is available during limited hours.

What time is check-out at 21C Museum Hotel St Louis ?

Check-out is at 11:00 AM.

Where is 21C Museum Hotel St Louis located?

Located in Downtown West, this luxury hotel is within a 10-minute walk of Washington Avenue Historic District, Enterprise Center, and City Museum. St. Louis Union Station and America's Center Convention Complex are also within 15 minutes. 8th and Pine Station is 13 minutes by foot and St. Louis Gateway Station is 14 minutes.

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21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 842 out of 1167 reviews
Rating 8 - Good. 180 out of 1167 reviews
Rating 6 - Okay. 66 out of 1167 reviews
Rating 4 - Poor. 34 out of 1167 reviews
Rating 2 - Terrible. 45 out of 1167 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Dominique

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and quiet and the rooms look just like the picture! Check in was fast.
Stayed 1 night in Jun 2025

10/10 Excellent

Robert

Liked: Cleanliness, property conditions & facilities
Good hotel located within walking distance of the ballpark, arch, and numerous other parks.
Stayed 2 nights in May 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, amenities, property conditions & facilities
The staff was amazing, room was awesome. Very close to the convention center
Stayed 5 nights in May 2025

10/10 Excellent

Cristina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely historic hotel. Amenities - pool and fitness center were excellent. Walkable to the City Museum. Would definitely stay here again.
Stayed 1 night in May 2025

10/10 Excellent

Jessica

Liked: Staff & service, amenities, property conditions & facilities
Great location, wonderful staff
Stayed 2 nights in Apr 2025

10/10 Excellent

Ryan

Liked: Cleanliness, amenities, property conditions & facilities
This place has everything. Great food, great coffee, outstanding gym and pool area, and the rooms are top notch. Friendly and knowledgeable staff throughout. City Museum, Stadiums, and Arch all within walking distance. If you are staying in downtown St. Louis, I don't see another option.
Stayed 2 nights in May 2025

10/10 Excellent

Julian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the property! Staff and amenities were too tier! Only thing I would recommend is security on site to stop homeless from approaching guests.
Stayed 2 nights in Jun 2025

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I always love staying at this hotel! The decor is beautiful and the drinks and food are top notch!
Stayed 1 night in Apr 2025

8/10 Good

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Great place in St. Louis.
Stayed 1 night in Apr 2025

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular interior! Good service. Would stay here again and highly recommend:)
Stayed 1 night in May 2025

10/10 Excellent

Denise

Liked: Cleanliness, amenities, property conditions & facilities
The art in house was cool! I also liked the restaurant. My room was comfortable and quiet.
Stayed 1 night in May 2025

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff and lobby bar
Stayed 4 nights in Mar 2025

10/10 Excellent

Sandra

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our two nights at this hotel. The property was nice and we were able to walk to Enterprise stadium easily.
Stayed 2 nights in Apr 2025

10/10 Excellent

Dallas

Liked: Cleanliness, amenities, property conditions & facilities
Had a great stay!
Stayed 1 night in Feb 2025

10/10 Excellent

Latisha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice and comfortable hotel.
Stayed 2 nights in Jan 2025

10/10 Excellent

Connor

Wonderful
Stayed 2 nights in May 2025

6/10 Okay

Jessica

Liked: Cleanliness, amenities
Disliked: Staff & service
Looks good and the toiletries brand is amazing
Stayed 1 night in Apr 2025

10/10 Excellent

Payton

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff were amazing. Highly recommend this hotel. This is the best hotel I’ve ever stayed at.
Stayed 1 night in Apr 2025

10/10 Excellent

David Michael

Liked: Cleanliness, amenities, property conditions & facilities
Great property
Stayed 4 nights in Apr 2025

10/10 Excellent

Staci

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Above and beyond guest service. Awesome deco. Highly recommend.
Stayed 1 night in May 2025

10/10 Excellent

Samuel

Liked: Cleanliness, staff & service, property conditions & facilities
It’s easy to walk to most every venue I go to downtown. The hotel is amazingly beautiful.
Stayed 1 night in Apr 2025

10/10 Excellent

Joni

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular restaurant, comfortable room, good museum, and it feels safe. The elevator has keyed access to each floor.
Stayed 2 nights in Apr 2025

10/10 Excellent

Colleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Welcoming, kind staff. So enjoyed our stay.
Stayed 2 nights in Mar 2025

10/10 Excellent

Deidra

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the stay and the Museum was an extra nice touch.
Stayed 1 night in Feb 2025

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fun hotel with an amazing restaurant and a lovely spa area