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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with a fitness center and a steam room

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Photo gallery for 21C Museum Hotel St Louis

Classic architecture with a grand entrance and evenly spaced windows.
Relax in a classic room with a large pool table, elegant curtains, and a chandelier.
Enjoy a luxurious bar experience with a curved countertop, comfortable seating, and a vibrant mural.
Relax by the pool surrounded by a comfortable seating area and natural light.
Experience the grandeur of our multi-level atrium, featuring a basketball court and balcony with a railing.

Popular amenities

  • Bar

Room options

Available filters for rooms
Showing 15 of 15 rooms

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | 1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.4 out of 10
Exceptional
(64 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

8.4 out of 10
Very good
(18 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Shower/tub combination
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(23 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.0 out of 10
Wonderful
(17 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Hair dryer
Shower/tub combination
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the neighborhood

Map
1528 Locust street, St. Louis, MO, 63103

What's nearby

  • St. Louis Union Station - 6 min walk - 0.4 miles
  • Enterprise Center - 6 min walk - 0.4 miles
  • City Museum - 6 min walk - 0.4 miles
  • Busch Stadium - 14 min walk - 0.8 miles
  • Gateway Arch - 2 min drive - 1.1 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel near St. Louis Union Station
Close to City Museum and Enterprise Center, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services, and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business center, guests can connect to free in-room WiFi.
You'll also enjoy the following perks during your stay:
  • An indoor pool
  • Cooked-to-order breakfast (surcharge), valet parking (surcharge), and an elevator
  • A vending machine, smoke-free premises, and a billiards/pool table
  • Luggage storage, meeting rooms, and ATM/banking services
  • Guest reviews speak highly of the dining options, pool, and helpful staff
Room features
All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks like free WiFi and desk chairs. Guest reviews highly rate the clean rooms at the property.
More amenities include:
  • Free toiletries and hair dryers
  • Flat-screen TVs with premium channels
  • Wardrobes/closets, heating, and daily housekeeping

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Does 21C Museum Hotel St Louis have a pool?

Yes, this property has an indoor pool.

Is 21C Museum Hotel St Louis pet-friendly?

Yes, dogs are allowed at this property. There's a fee of USD 100 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21C Museum Hotel St Louis ?

Valet parking is available for USD 50 per day.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM. Late check-in is available during limited hours.

What time is check-out at 21C Museum Hotel St Louis ?

Check-out is at 11:00 AM.

Where is 21C Museum Hotel St Louis located?

Located in Downtown West, this luxury hotel is within a 10-minute walk of Washington Avenue Historic District, City Museum, and Enterprise Center. St. Louis Union Station and America's Center Convention Complex are also within 15 minutes. 8th and Pine Station is 13 minutes by foot and St. Louis Gateway Station is 14 minutes.

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21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 919 out of 1270 reviews
Rating 8 - Good. 190 out of 1270 reviews
Rating 6 - Okay. 73 out of 1270 reviews
Rating 4 - Poor. 38 out of 1270 reviews
Rating 2 - Terrible. 50 out of 1270 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Jeffrey

Liked: Cleanliness
Great place to stay.
Stayed 1 night in Jun 2025

10/10 Excellent

rebecca

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great location
Stayed 1 night in Jun 2025

10/10 Excellent

Lima Rose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay
Stayed 1 night in Jun 2025

10/10 Excellent

Nicole

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was absolutely beautiful and so unique. The staff was so amazing and friendly, and the rooms were beautiful. We will definitely be repeat guests.
Stayed 3 nights in Jul 2025

10/10 Excellent

Shamiyer

I loved my stay the room was perfect and very comfortable and clean
Stayed 1 night in Jul 2025

10/10 Excellent

Will

Liked: Cleanliness, amenities, property conditions & facilities
Great place, decor, art, and people
Stayed 2 nights in Jun 2025

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was very clean and easily accessible between restaurant, room, and galleries.
Stayed 1 night in Jun 2025

10/10 Excellent

Mike

Liked: Amenities
Museum is fabulous, lobby and room are terrific!
Stayed 1 night in Jul 2025

8/10 Good

Roger

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful building and the atmosphere was just relaxing and fun
Stayed 2 nights in Jun 2025

10/10 Excellent

Tabitha

Liked: Cleanliness, amenities, property conditions & facilities
Great value. Great restaurant. Great staff!
Stayed 2 nights in Jun 2025

10/10 Excellent

Julie

Liked: Amenities
Everything about this hotel was magical! Food is fove star service people rooms. Saunna workout room and it's beautiful!
Stayed 2 nights in Jul 2025

8/10 Good

kayla

Liked: Amenities
Not a great area but a great hotel
Stayed 1 night in Jun 2025

10/10 Excellent

Korie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
very nice hotel felt worth the money
Stayed 1 night in Jun 2025

10/10 Excellent

Nicole

Liked: Cleanliness, property conditions & facilities
Thebhotel itself was beautiful akd clean. Parking, and the flooded streets made it miserable to get around directly around the hotel
Stayed 1 night in Jun 2025

10/10 Excellent

Julio

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent service
Stayed 1 night in Jul 2025

10/10 Excellent

Rebecca

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kevin was especially helpful and good to find a fellow LFC supporter !
Stayed 2 nights in Jul 2025

8/10 Good

Tyson

Liked: Cleanliness, amenities, property conditions & facilities
All that’s needed is access to parking. The paid lot in the rear was cramped. Love the hotel and staff.
Stayed 2 nights in Jun 2025

10/10 Excellent

Hasani

Liked: Cleanliness, amenities, property conditions & facilities
The pool and patio area was beautiful. Everything including the staff was 10/10.
Stayed 2 nights in Jun 2025

10/10 Excellent

Aisha

Liked: Cleanliness, amenities, property conditions & facilities
Lovely
Stayed 3 nights in Jun 2025

2/10 Terrible

Shanzaib

Disliked: Cleanliness, amenities, property conditions & facilities
Worst hotel and staff ever
Stayed 5 nights in Jul 2025

10/10 Excellent

Robert

Liked: Cleanliness, property conditions & facilities
Good hotel located within walking distance of the ballpark, arch, and numerous other parks.
Stayed 2 nights in May 2025

10/10 Excellent

Dominique

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and quiet and the rooms look just like the picture! Check in was fast.
Stayed 1 night in Jun 2025

10/10 Excellent

Kenyatta

Liked: Cleanliness, amenities, property conditions & facilities
This property was a wonderful place to stay. Even though the museum in side was booked two of the three days I was there. I got a chance to see it before heading home.
Stayed 2 nights in Jun 2025

10/10 Excellent

Timothy

Liked: Amenities, property conditions & facilities
Nice
Stayed 1 night in Jun 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, amenities, property conditions & facilities
The staff was amazing, room was awesome. Very close to the convention center
Stayed 5 nights in May 2025