
Business Hotels in St. Louis 2025
Featured St. Louis Business Hotels

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay

City Place St. Louis Downtown
200 N 4Th Street, St. Louis, MO
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Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
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Courtyard by Marriott St Louis Creve Coeur
828 N New Ballas Rd, St. Louis, MO
Fully refundableReserve now, pay when you stay

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay

The Wildwood Hotel
2801 Fountain Pl, Wildwood, MO
Fully refundableReserve now, pay when you stay

La Quinta Inn & Suites by Wyndham St. Louis Westport
11805 Lackland Rd, Maryland Heights, MO

Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd, Maryland Heights, MO

Hyatt Place St. Louis/Chesterfield
333 Chesterfield Center East, Chesterfield, MO
Fully refundableReserve now, pay when you stay

Holiday Inn Express St. Louis Arpt - Maryland Hgts by IHG
13615 Riverport Drive, I-70 & Earth City Expswy, Maryland Heights, MO

Hilton Pennywell St. Louis at the Arch
400 Olive St, St. Louis, MO
Fully refundableReserve now, pay when you stay

OYO Hotel St. Louis Downtown City Center MO
400 S 14th St, St. Louis, MO

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street, St. Louis, MO
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Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
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Home2 Suites by Hilton St. Charles St.Louis
32 Research Park Circle, St. Charles, MO

Courtyard by Marriott St Louis Westport Plaza
11888 Westline Industrial Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.