Business Hotels in St. Louis 2025
Featured St. Louis Business Hotels
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
City Place St. Louis Downtown
200 N 4Th Street St. Louis MO
Save an average of 15% on thousands of hotels when you're signed in
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
Courtyard by Marriott St Louis Creve Coeur
828 N New Ballas Rd St. Louis MO
Fully refundableReserve now, pay when you stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
The Wildwood Hotel
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
La Quinta Inn & Suites by Wyndham St. Louis Westport
11805 Lackland Rd Maryland Heights MO
Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd Maryland Heights MO
Hyatt Place St. Louis/Chesterfield
333 Chesterfield Center East Chesterfield MO
Fully refundableReserve now, pay when you stay
Holiday Inn Express St. Louis Arpt - Maryland Hgts by IHG
13615 Riverport Drive Maryland Heights MO
Hilton Pennywell St. Louis at the Arch
400 Olive St St. Louis MO
Fully refundableReserve now, pay when you stay
OYO Hotel St. Louis Downtown City Center MO
400 S 14th St St. Louis MO
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
Home2 Suites by Hilton St. Charles St.Louis
32 Research Park Circle St. Charles MO
Courtyard by Marriott St Louis Westport Plaza
11888 Westline Industrial Dr Maryland Heights MO
Fully refundableReserve now, pay when you stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.