San Francisco Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
San Francisco Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Renaissance Panama City Hotel
Bella Vista
Price was $963, price is now $833 per person
$833
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a casino. Popular attractions Via Espana and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Price was $1,805, price is now $1,290 per person
$1,290
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cinta Costera and Amador Causeway are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,196, price is now $884 per person
$884
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Via Espana and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,171, price is now $902 per person
$902
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Avenida Balboa and Multiplaza Pacific Mall are located nearby.
Riande Aeropuerto Hotel & Casino
Price was $1,189, price is now $940 per person
$940
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
W Panama
Bella Vista
Price was $1,286, price is now $1,059 per person
$1,059
per person
May 7 - May 12
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Via Espana and Avenida Balboa are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to San Francisco
View all tripsTop Hotel Deals
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
0.75 km from San Francisco
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
0.58 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
1.93 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
1.05 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Aloft Panama
Via Israel & Calle 76 Panama City Panama
0.62 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
1.92 km from San Francisco
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
2.01 km from San Francisco
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
2.31 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P Panama City
1.71 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
2.07 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Boutique Apartments Atlapa
C. 76 Este Panama City Provincia de Panamá
0.49 km from San Francisco
Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
1.99 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
15.65 km from San Francisco
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Jul 1 - Sun, Jul 5
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$268 Roundtrip, found 1 day ago
$268
Roundtrip
found 1 day ago
Sun, Jun 28 - Thu, Jul 2
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Sat, Jun 6 - Mon, Jun 8
MIA
Miami Intl.
PTY
Tocumen Intl.
$300 Roundtrip, found 19 hours ago
$300
Roundtrip
found 19 hours ago
Sun, May 10 - Thu, May 14
MIA
Miami Intl.
PTY
Tocumen Intl.
$412 Roundtrip, found 3 days ago
$412
Roundtrip
found 3 days ago
Sun, May 10 - Thu, May 14
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$655 Roundtrip, found 3 days ago
$655
Roundtrip
found 3 days ago