San Francisco Vacation Packages for 2026
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San Francisco Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,248, price is now $975 per person
$975
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Price was $1,682, price is now $1,250 per person
$1,250
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Megapolis Hotel Panamá
San Francisco
Price was $1,460, price is now $1,115 per person
$1,115
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Price was $1,484, price is now $1,242 per person
$1,242
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
Price was $1,358, price is now $1,137 per person
$1,137
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,184, price is now $992 per person
$992
per person
Jun 26 - Jun 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
2.31 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
1.05 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Aloft Panama
Via Israel & Calle 76 Panama City Panama
0.62 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
0.58 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
1.92 km from San Francisco
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
1.93 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
0.75 km from San Francisco
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
2.01 km from San Francisco
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
2.07 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P Panama City
1.71 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Boutique Apartments Panamá Coco del Mar
Av. Cincuentenario Panama City Provincia de Panamá
1.23 km from San Francisco
Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall ...
Dovle Residences by HMS-Preferred Member
Vía Cincuentenario Panama City Provincia de Panamá
1.57 km from San Francisco
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
1.99 km from San Francisco
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Jul 1 - Sun, Jul 5
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Wed, Jul 1 - Sun, Jul 5
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$275 Roundtrip, found 1 day ago
$275
Roundtrip
found 1 day ago
Sun, May 10 - Mon, May 18
MIA
Miami Intl.
PTY
Tocumen Intl.
$473 Roundtrip, found 3 days ago
$473
Roundtrip
found 3 days ago
Tue, Jul 28 - Sat, Aug 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$551 Roundtrip, found 1 day ago
$551
Roundtrip
found 1 day ago
Thu, Aug 20 - Thu, Aug 27
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$596 Roundtrip, found 9 hours ago
$596
Roundtrip
found 9 hours ago