San Francisco Vacation Packages for 2025
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San Francisco Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel
Amador
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Waldorf Astoria Panama
Bella Vista
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Hotel Riu Plaza Panama
Bella Vista
per person
Sep 6 - Sep 10
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Bristol Panama, a Registry Collection Hotel
Bella Vista
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
MARINN PLACE Financial District
Bella Vista
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
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Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
0.75 km from San Francisco
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Calle Punta Colon, Punta Pacifica, Panama City, Panama
1.9 km from San Francisco
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
Ramada Plaza By Wyndham Panama Punta Pacífica
Via Israel y Calle 71, San Francisco, Panama City, Panama
0.58 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Megapolis Hotel Panamá
Avenida Balboa, Panama City
2.07 km from San Francisco
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro, Panama City, Panama
2.01 km from San Francisco
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
1.92 km from San Francisco
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
2.31 km from San Francisco
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P, Panama City
1.71 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall, Panama City, Panama
1.05 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Aloft Panama
Via Israel & Calle 76, Panama City, Panama
0.64 km from San Francisco
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Boutique Apartments Panamá Coco del Mar
Av. Cincuentenario, Panama City, Provincia de Panamá
1.23 km from San Francisco
Stay at this 3.5-star apartment in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Albrook Shopping Mall and Multiplaza ...
San Francisco by Wynwood House
C. 73 Este, Panama City, Provincia de Panamá
0.06 km from San Francisco
Stay at this 4-star aparthotel in Panama City. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
1.99 km from San Francisco
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Fri, Jul 25 - Fri, Aug 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$276 Roundtrip, found 4 days ago
$276
Roundtrip
found 4 days ago
Sat, Jul 26 - Sat, Aug 2
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 4 days ago
$290
Roundtrip
found 4 days ago
Tue, Jul 22 - Wed, Jul 30
MIA
Miami Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 4 days ago
$290
Roundtrip
found 4 days ago
Thu, Jul 17 - Tue, Jul 22
MIA
Miami Intl.
PTY
Tocumen Intl.
$373 Roundtrip, found 16 hours ago
$373
Roundtrip
found 16 hours ago
Fri, Jul 25 - Fri, Aug 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$373 Roundtrip, found 4 days ago
$373
Roundtrip
found 4 days ago
Best points of interest in Panama City
- Multiplaza Pacific Mall Vacations
- Avenida Balboa Vacations
- ATLAPA Conventions Center Vacations
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- Colonial Religious Art Museum Vacations
- Albrook Shopping Mall Vacations
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