2025 4 Star Hotels in Downtown San Francisco

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Featured Downtown San Francisco 4 Star Hotels

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
Hyatt Regency San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Hilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Club Quarters Hotel in San Francisco
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4 out of 5
50 3rd St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Hyatt Regency San Francisco Downtown SOMA
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street, San Francisco, CA
Fully refundable
InterContinental Mark Hopkins by IHG
InterContinental San Francisco by IHG

InterContinental San Francisco by IHG

4 out of 5
888 Howard Street, San Francisco, CA
Fully refundable
InterContinental San Francisco by IHG
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4 out of 5
495 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The Clift Royal Sonesta San Francisco
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

4.5 out of 5
335 Powell Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
The Westin St. Francis San Francisco on Union Square
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4 out of 5
450 Powell Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Beacon Grand, A Union Square Hotel
See all 991 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.