2025 4 Star Hotels in Downtown San Francisco

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Featured Downtown San Francisco 4 Star Hotels

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Hyatt Regency San Francisco
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Club Quarters Hotel in San Francisco
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St, San Francisco, CA
Parc 55 San Francisco - A Hilton Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Hilton San Francisco Financial District
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4 out of 5
50 3rd St, San Francisco, CA
Hyatt Regency San Francisco Downtown SOMA
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St., San Francisco, CA
Hilton San Francisco Union Square
citizenM San Francisco Union Square

citizenM San Francisco Union Square

4 out of 5
72 Ellis Street, San Francisco, CA
citizenM San Francisco Union Square
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4 out of 5
495 Geary St, San Francisco, CA
The Clift Royal Sonesta San Francisco
Omni San Francisco Hotel

Omni San Francisco Hotel

4.5 out of 5
500 California St, San Francisco, CA
Omni San Francisco Hotel
See all 977 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.