
Medical Center District Vacation Packages for 2025
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Medical Center District Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
Northwest Side
Price was $657, price is now $530 per person
$530
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Six Flags Fiesta Texas and The Shops of La Cantera are located nearby.

La Luz
Downtown San Antonio
Price was $941, price is now $651 per person
$651
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Stay at this 3-star hotel in San Antonio. Enjoy free WiFi, laundry facilities, and premium bedding. Popular attractions Alamo and River Walk are located nearby.

Home2 Suites by Hilton San Antonio Riverwalk, TX
Downtown San Antonio
Price was $880, price is now $663 per person
$663
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions River Walk and Alamo are located nearby.

Hyatt Regency Hill Country Resort and Villas
Far West Side
Price was $1,364, price is now $1,030 per person
$1,030
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hill Country Golf Club and Aquatica San Antonio Waterpark are located nearby.

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Far West Side
Price was $733, price is now $556 per person
$556
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and a lazy river. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Hill Country Golf Club and Aquatica San Antonio Waterpark are located nearby.

Crockett Hotel
Downtown San Antonio
Price was $776, price is now $607 per person
$607
per person
Jan 29 - Feb 3
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to San Antonio (SAT)
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant in our reviews. Popular attractions Alamo and River Walk are located nearby.
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See all available trips from Columbus to Medical Center District
View all tripsTop Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
2.3 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
2.88 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...

Fairfield Inn & Suites by Marriott San Antonio Medical Center
7203 Wurzbach Road San Antonio TX
0.97 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
1.49 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...

Crockett Hotel
320 Bonham San Antonio TX
12.65 km from Medical Center District
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...

Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
12.1 km from Medical Center District
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...

Riverwalk Plaza
100 Villita Street San Antonio TX
12.3 km from Medical Center District
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
12.29 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
11.28 km from Medical Center District
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and a lazy river. Our guests praise the pool and the helpful staff in ...

Omni La Mansion del Rio
112 College St San Antonio TX
12.28 km from Medical Center District
Book a stay at this spa hotel in San Antonio. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...

Hotel Contessa
306 W Market Street San Antonio TX
12.51 km from Medical Center District
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...

Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
12.63 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

Hyatt Regency San Antonio Riverwalk
123 Losoya St San Antonio TX
12.41 km from Medical Center District
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
Don't see what you're looking for?
See all available properties in Medical Center District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 3 - Wed, Jan 7
MSP
Minneapolis - St. Paul Intl.
SAT
San Antonio Intl.
$137 Roundtrip, found 6 days ago
$137
Roundtrip
found 6 days ago

Mon, Dec 29 - Wed, Dec 31
LAX
Los Angeles Intl.
SAT
San Antonio Intl.
$174 Roundtrip, found 2 days ago
$174
Roundtrip
found 2 days ago

Fri, Dec 12 - Sun, Dec 14
SEA
Seattle - Tacoma Intl.
SAT
San Antonio Intl.
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago

Fri, Dec 12 - Sun, Dec 14
SEA
Seattle - Tacoma Intl.
SAT
San Antonio Intl.
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago

Fri, Dec 12 - Sun, Dec 14
SEA
Seattle - Tacoma Intl.
SAT
San Antonio Intl.
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago

