
South Carolina Midlands Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
South Carolina Midlands Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Sands Ocean Club Resort
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3-star beach resort in Myrtle Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the bar in our reviews. Popular attractions Broadway at the Beach and Apache Pier are located nearby.

Dunes Village Resort
Save 100% on your flight
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3.5-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the bar in our reviews. Popular attractions Broadway at the Beach and Myrtle Beach Boardwalk are located nearby.

Crown Reef Beach Resort and Waterpark
Save 100% on your flight
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.

The Caravelle Resort
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, a beach locale, and 3 hot tubs. Our guests praise the clean rooms in our reviews. Popular attractions Broadway at the Beach and Myrtle Beach Boardwalk are located nearby.

Paradise Resort
Save 100% on your flight
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.

Bluegreen Vacations Harbour Lights, Ascend Resort Collection
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
New York (LGA) to Myrtle Beach (MYR)
Stay at this 3-star family-friendly hotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Broadway at the Beach and Myrtle Beach Boardwalk are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to South Carolina Midlands
View all tripsTop Hotel Deals

Tru By Hilton Columbia Downtown
400 Gervais Street, Building 2, Columbia, SC
18.85 km from city center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and Williams Brice ...

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr, Columbia, SC
27.9 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
13.82 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Millwood ...

Clarion Pointe Near University
1106 N. Anderson Road, Rock Hill, SC
100.37 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr, Columbia, SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
95.06 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...

Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd, Columbia, SC
14.14 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive, Columbia, SC
7.87 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Cambria Hotel Columbia Downtown The Vista
1000 Lady Street, Columbia, SC
17.89 km from city center
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

La Quinta Inn & Suites by Wyndham Rock Hill
1235 Springdale Rd, Rock Hill, SC
96.7 km from city center
Stay at this 3-star business-friendly hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Hyatt Place Columbia/Harbison
1130 Kinley Road, Irmo, SC
27.82 km from city center
Stay at this 3-star business-friendly hotel in Irmo. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 21 - Wed, Oct 22
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$70 Roundtrip, found 1 day ago
$70
Roundtrip
found 1 day ago

Wed, Aug 6 - Tue, Aug 12
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$106 Roundtrip, found 3 hours ago
$106
Roundtrip
found 3 hours ago

Wed, Aug 20 - Thu, Aug 21
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$148 Roundtrip, found 4 days ago
$148
Roundtrip
found 4 days ago

Tue, Aug 19 - Tue, Aug 26
LGA
LaGuardia
CAE
Columbia Metropolitan
$167 Roundtrip, found 6 days ago
$167
Roundtrip
found 6 days ago
Best neighborhoods in South Carolina Midlands
Best points of interest in South Carolina Midlands
- Fort Jackson Vacations
- Carowinds Theme Park Vacations
- University of South Carolina Vacations
- Williams Brice Stadium Vacations
- Riverbanks Zoo and Garden Vacations
- Darlington Raceway Vacations
- Colonial Life Arena Vacations
- Florence Civic Center Vacations
- Congaree National Park Vacations
- Columbia Metropolitan Convention Center Vacations
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All accommodation types in South Carolina Midlands
More Types of Hotels
- Hotels with WiFi in South Carolina Midlands
- Hotels with Air Conditioning in South Carolina Midlands
- Hotel with wifi in South Carolina Midlands
- Family Hotels in South Carolina Midlands
- Hotels with Complimentary Breakfast in South Carolina Midlands
- Hotels with a Pool in South Carolina Midlands
- Pet-friendly Hotels in South Carolina Midlands
- Smoke Free Hotels in South Carolina Midlands
- Cheap Hotels in South Carolina Midlands
- Hotels with Bars in South Carolina Midlands
- Luxury Hotels in South Carolina Midlands
- Hotels with Hot Tubs in South Carolina Midlands
- Hotels with an Indoor Pool in South Carolina Midlands
- Resorts & Hotels with Spas in South Carolina Midlands
- Lakefront Hotels in South Carolina Midlands
- Beach Hotels in South Carolina Midlands
- Hotels with smoking rooms in South Carolina Midlands
- Hotels with Balconies in South Carolina Midlands
- Hotel with a Concierge in South Carolina Midlands
- Hotels with Fireplaces in South Carolina Midlands
- Hotels with Tennis Courts in South Carolina Midlands
- Hotels with Free Airport Shuttle in South Carolina Midlands
- Adults Only Resorts & Hotels in South Carolina Midlands
- Hotels with Early Check-in in South Carolina Midlands
- Casinos in South Carolina Midlands