
South Carolina Midlands Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
27.9 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
13.82 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...

Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
17.88 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...

Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd Columbia SC
14.14 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

Tru by Hilton Rock Hill
800 Galleria Blvd. Rock Hill SC
96.84 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Clarion Pointe Rock Hill Near University
1106 N. Anderson Road Rock Hill SC
100.34 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Cambria Hotel Columbia Downtown The Vista
1000 Lady Street Columbia SC
17.89 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
16.93 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Sleep Inn Columbia
1901 Rockland Rd Columbia SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
95.56 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 3 - Tue, Mar 10
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$79 Roundtrip, found 1 day ago
$79
Roundtrip
found 1 day ago

Tue, Jan 20 - Sat, Jan 24
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$82 Roundtrip, found 1 day ago
$82
Roundtrip
found 1 day ago

Sat, Feb 7 - Tue, Feb 10
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$139 Roundtrip, found 15 hours ago
$139
Roundtrip
found 15 hours ago

Wed, Feb 4 - Sat, Feb 7
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$159 Roundtrip, found 15 hours ago
$159
Roundtrip
found 15 hours ago

Fri, Aug 7 - Fri, Aug 21
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago

