
South Carolina Midlands Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
South Carolina Midlands Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Charlotte Marriott City Center
Uptown Charlotte
Save 100% on your flight
Price was $810, price is now $542 per person
$542
per person
Aug 25 - Aug 29
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Charlotte (CLT)
Book a stay at this business-friendly hotel in Charlotte. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Spectrum Center and Bank of America Stadium are located nearby.

Westgate Myrtle Beach Oceanfront Resort
Save 100% on your flight
Price was $1,959, price is now $1,053 per person
$1,053
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
Book a stay at this beach resort in Myrtle Beach. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Family Kingdom Amusement Park and Myrtle Beach Boardwalk are located nearby.

Marina Inn Grande Dunes Condos & Suites
Save 100% on your flight
Price was $2,211, price is now $1,419 per person
$1,419
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
Book a stay at this luxury aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Ripley's Aquarium and Broadway at the Beach are located nearby.

Marina Inn At Grande Dunes
Save 100% on your flight
Price was $2,211, price is now $1,432 per person
$1,432
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
Book a stay at this luxury resort in Myrtle Beach. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Ripley's Aquarium and Broadway at the Beach are located nearby.

Dunes Village Resort
Price was $1,447, price is now $1,042 per person
$1,042
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
Book a stay at this beach aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Ripley's Aquarium and Broadway at the Beach are located nearby.

Caribbean Resort & Villas
Price was $1,335, price is now $985 per person
$985
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
Book a stay at this beach hotel in Myrtle Beach. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ripley's Aquarium and Broadway at the Beach are located nearby.
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See all available trips from Columbus to South Carolina Midlands
View all tripsTop Hotel Deals

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
27.9 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

Courtyard by Marriott Columbia Downtown at USC
630 Assembly St Columbia SC
17.88 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
13.82 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and South ...

Tru By Hilton Columbia Downtown
400 Gervais Street Columbia SC
18.85 km from city center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and South Carolina ...

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
95.04 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street Columbia SC
18.16 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive Columbia SC
7.87 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Clarion Pointe Rock Hill Near University
1106 N. Anderson Road Rock Hill SC
100.34 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Sleep Inn Columbia
1901 Rockland Rd Columbia SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
14.09 km from city center
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Cambria Hotel Columbia Downtown The Vista
1000 Lady Street Columbia SC
17.89 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 22 - Tue, Aug 25
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$170 Roundtrip, found 4 hours ago
$170
Roundtrip
found 4 hours ago

Tue, Sep 8 - Sat, Sep 12
BOS
Logan Intl.
CAE
Columbia Metropolitan
$251 Roundtrip, found 16 hours ago
$251
Roundtrip
found 16 hours ago

Wed, Oct 7 - Sat, Oct 10
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$261 Roundtrip, found 2 days ago
$261
Roundtrip
found 2 days ago

Thu, Sep 10 - Tue, Sep 22
DAL
Love Field
CLT
Charlotte-Douglas Intl.
$305 Roundtrip, found 2 days ago
$305
Roundtrip
found 2 days ago

Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
CAE
Columbia Metropolitan
$337 Roundtrip, found 2 days ago
$337
Roundtrip
found 2 days ago

