
South Carolina Midlands Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr, Columbia, SC
27.9 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

Sleep Inn Columbia
1901 Rockland Rd, Columbia, SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr, Columbia, SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd, Columbia, SC
14.09 km from city center
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive, Columbia, SC
7.87 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Clarion Pointe Near University
1106 N. Anderson Road, Rock Hill, SC
100.34 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Tru By Hilton Columbia Downtown
400 Gervais Street, Building 2, Columbia, SC
18.85 km from city center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...

Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd, Columbia, SC
14.14 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...

Cambria Hotel Columbia Downtown The Vista
1000 Lady Street, Columbia, SC
17.89 km from city center
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct, Columbia, SC
27.42 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Courtyard by Marriott Columbia Downtown at USC
630 Assembly St, Columbia, SC
17.88 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...

Super 8 by Wyndham Harbison/Parkridge Hospital
411 Piney Grove Rd, Columbia, SC
26.3 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 13 - Tue, Nov 18
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$65 Roundtrip, found 1 day ago
$65
Roundtrip
found 1 day ago

Thu, Nov 13 - Tue, Nov 18
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$70 Roundtrip, found 1 day ago
$70
Roundtrip
found 1 day ago

Mon, Nov 17 - Tue, Nov 18
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$159 Roundtrip, found 6 days ago
$159
Roundtrip
found 6 days ago

Mon, Nov 24 - Wed, Dec 3
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$174 Roundtrip, found 3 days ago
$174
Roundtrip
found 3 days ago

Sun, Nov 16 - Tue, Nov 25
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$295 Roundtrip, found 6 days ago
$295
Roundtrip
found 6 days ago

