South Carolina Midlands Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
South Carolina Midlands Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Caribbean Resort & Villas
Price was $1,005, price is now $777 per person
$777
per person
Apr 18 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Akron (CAK) to Myrtle Beach (MYR)
Book a stay at this beach hotel in Myrtle Beach. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Myrtle Beach Boardwalk and Myrtle Beach Beaches are located nearby.
The Ellie Beach Resort Myrtle Beach, Tapestry By Hilton
Save 100% on your flight
Price was $1,242, price is now $886 per person
$886
per person
Apr 18 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Akron (CAK) to Myrtle Beach (MYR)
Book a stay at this beach resort in Myrtle Beach. Enjoy an outdoor pool, 2 restaurants, and a beach locale. Popular attractions Myrtle Beach Boardwalk and Myrtle Beach State Park are located nearby.
DoubleTree Resort by Hilton Myrtle Beach Oceanfront
Save 100% on your flight
Price was $1,338, price is now $965 per person
$965
per person
Apr 22 - Apr 28
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Myrtle Beach (MYR)
Book a stay at this beach resort in Myrtle Beach. Enjoy free WiFi, 2 indoor pools, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Myrtle Beach State Park are located nearby.
Grand Atlantic Ocean Resort
Price was $1,083, price is now $827 per person
$827
per person
Apr 18 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Akron (CAK) to Myrtle Beach (MYR)
Book a stay at this beach hotel in Myrtle Beach. Enjoy free WiFi, 2 outdoor pools, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Family Kingdom Amusement Park are located nearby.
Crown Reef Beach Resort and Waterpark
Price was $1,075, price is now $836 per person
$836
per person
Apr 18 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Akron (CAK) to Myrtle Beach (MYR)
Book a stay at this beach aparthotel in Myrtle Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Myrtle Beach State Park are located nearby.
Westgate Myrtle Beach Oceanfront Resort
Price was $1,264, price is now $992 per person
$992
per person
Apr 22 - Apr 28
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Myrtle Beach (MYR)
Book a stay at this beach resort in Myrtle Beach. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Myrtle Beach Boardwalk and Family Kingdom Amusement Park are located nearby.
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See all available trips from Columbus to South Carolina Midlands
View all tripsTop Hotel Deals
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
27.9 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
13.82 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct Columbia SC
27.42 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive Columbia SC
23.17 km from city center
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and AMF ...
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
95.56 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
16.93 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
101.82 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street Columbia SC
18.16 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
14.09 km from city center
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Country Inn & Suites by Radisson, Columbia at Harbison, SC
414 Piney Grove Road Columbia SC
26.25 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Apr 15 - Wed, Apr 29
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$80 Roundtrip, found 6 days ago
$80
Roundtrip
found 6 days ago
Wed, Apr 8 - Tue, Apr 14
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$82 Roundtrip, found 1 day ago
$82
Roundtrip
found 1 day ago
Wed, Apr 15 - Tue, May 5
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$179 Roundtrip, found 4 days ago
$179
Roundtrip
found 4 days ago
Tue, Apr 14 - Tue, Apr 28
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$199 Roundtrip, found 6 days ago
$199
Roundtrip
found 6 days ago
Mon, Aug 31 - Mon, Sep 7
DEN
Denver Intl.
CAE
Columbia Metropolitan
$349 Roundtrip, found 4 days ago
$349
Roundtrip
found 4 days ago