South Carolina Midlands Vacation Packages for 2025

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South Carolina Midlands Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Sands Ocean Club Resort

Sands Ocean Club Resort

3 out of 5
Save 100% on your flight
per person
Aug 4 - Aug 8
found 19 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 3-star beach resort in Myrtle Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the bar in our reviews. Popular attractions Broadway at the Beach and Apache Pier are located nearby.

Westgate Myrtle Beach Oceanfront Resort

Westgate Myrtle Beach Oceanfront Resort

3.5 out of 5
Save 100% on your flight
per person
Aug 4 - Aug 8
found 18 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 3.5-star beach resort in Myrtle Beach. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.

Marina Inn At Grande Dunes

Marina Inn At Grande Dunes

4.5 out of 5
Save 100% on your flight
per person
Aug 4 - Aug 8
found 19 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 4.5-star luxury hotel in Myrtle Beach. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Broadway at the Beach and Apache Pier are located nearby.

Country Club Villas

Country Club Villas

3 out of 5
per person
Aug 4 - Aug 8
found 19 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 3-star aparthotel in Surfside Beach. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Myrtle Beach State Park and The Market Common are located nearby.

Crown Reef Beach Resort and Waterpark

Crown Reef Beach Resort and Waterpark

3 out of 5
per person
Aug 4 - Aug 8
found 19 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.

Camelot By the Sea

Camelot By the Sea

3 out of 5
per person
Aug 4 - Aug 8
found 18 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Myrtle Beach (MYR)
Stay at this 3-star beach apartment in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.

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Top Hotel Deals

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr, Columbia, SC
27.9 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St, Columbia, SC
17.88 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street, Columbia, SC
17.89 km from city center
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

3 out of 5
1538 Horseshoe Drive, Columbia, SC
7.87 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Clarion Pointe Near University

Clarion Pointe Near University

2.5 out of 5
1106 N. Anderson Road, Rock Hill, SC
100.37 km from city center
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street, Columbia, SC
16.93 km from city center
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and ...
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd, Columbia, SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr, Florence, SC
95.04 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr, Columbia, SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street, Columbia, SC
18.16 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street, Building 2, Columbia, SC
18.85 km from city center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and Williams Brice ...
Woodspring Suites Columbia - Irmo

Woodspring Suites Columbia - Irmo

2.5 out of 5
941 Columbiana Dr, Irmo, SC
29.14 km from city center
Stay at this hotel in Irmo. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Lake Murray and Irmo Community Park are located ...
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd, Columbia, SC
13.82 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Millwood ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Jul 22 - Tue, Jul 22
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$87 Roundtrip, found 4 days ago
$87
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Tue, Jul 22 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Tue, Jul 22, priced at $87 found 4 days ago
Spirit Airlines
Tue, Jun 10 - Tue, Jun 17
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$109 Roundtrip, found 1 day ago
$109
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Tue, Jun 10 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 17, priced at $109 found 1 day ago
Spirit Airlines
Sun, Jun 8 - Sat, Jun 14
DFW
Dallas-Fort Worth Intl.
CLT
Charlotte-Douglas Intl.
$122 Roundtrip, found 4 days ago
$122
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Sun, Jun 8 from Dallas-Fort Worth Intl. to Charlotte-Douglas Intl., returning Sat, Jun 14, priced at $122 found 4 days ago
Frontier Airlines
Wed, Jun 11 - Sat, Jun 14
PHL
Philadelphia Intl.
CLT
Charlotte-Douglas Intl.
$128 Roundtrip, found 5 days ago
$128
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Jun 11 from Philadelphia Intl. to Charlotte-Douglas Intl., returning Sat, Jun 14, priced at $128 found 5 days ago