South Carolina Midlands Vacation Packages for 2025
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South Carolina Midlands Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
hotel BLUE
Price was $575, price is now $430 per person
$430
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Myrtle Beach (MYR)
Stay at this 3-star beach hotel in Myrtle Beach. Enjoy a beach locale, 2 hot tubs, and 2 bars/lounges. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.
Marina Inn At Grande Dunes
Save 100% on your flight
Price was $1,093, price is now $727 per person
$727
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Myrtle Beach (MYR)
Stay at this 4.5-star luxury hotel in Myrtle Beach. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Broadway at the Beach and Apache Pier are located nearby.
Crown Reef Beach Resort and Waterpark
Price was $720, price is now $482 per person
$482
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.
North Beach Resort & Villas
Windy Hill
Price was $991, price is now $733 per person
$733
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Myrtle Beach (MYR)
Stay at this 4-star beach hotel in North Myrtle Beach. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Barefoot Landing and House of Blues Myrtle Beach are located nearby.
Grande Cayman Resort
Price was $659, price is now $515 per person
$515
per person
Oct 5 - Oct 11
found 11 hours ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Broadway at the Beach and Myrtle Beach Boardwalk are located nearby.
Camelot By the Sea
Price was $661, price is now $518 per person
$518
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Myrtle Beach (MYR)
Stay at this 3-star beach apartment in Myrtle Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Myrtle Beach Boardwalk and Broadway at the Beach are located nearby.
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See all available trips from Columbus to South Carolina Midlands
View all tripsTop Hotel Deals
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr, Columbia, SC
27.9 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
13.82 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Colonial ...
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr, Columbia, SC
8 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Cambria Hotel Columbia Downtown The Vista
1000 Lady Street, Columbia, SC
17.89 km from city center
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
98.94 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive, Columbia, SC
7.87 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Sleep Inn Columbia
1901 Rockland Rd, Columbia, SC
24 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct, Columbia, SC
27.42 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Tru By Hilton Columbia Downtown
400 Gervais Street, Building 2, Columbia, SC
18.85 km from city center
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...
Courtyard by Marriott Columbia Downtown at USC
630 Assembly St, Columbia, SC
17.88 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
Graduate by Hilton Columbia SC
1619 Pendleton Street, Columbia, SC
16.93 km from city center
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and ...
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd, Columbia, SC
14.09 km from city center
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
98.97 km from city center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sat, Nov 8 - Sat, Nov 15
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$80 Roundtrip, found 15 hours ago
$80
Roundtrip
found 15 hours ago
Tue, Nov 11 - Wed, Nov 12
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$90 Roundtrip, found 14 hours ago
$90
Roundtrip
found 14 hours ago
Sat, Nov 8 - Sat, Nov 15
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$139 Roundtrip, found 15 hours ago
$139
Roundtrip
found 15 hours ago
Sat, Nov 8 - Sat, Nov 15
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$139 Roundtrip, found 15 hours ago
$139
Roundtrip
found 15 hours ago
Sat, Nov 8 - Sat, Nov 15
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$139 Roundtrip, found 15 hours ago
$139
Roundtrip
found 15 hours ago