Santa Ana Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Photo by Alicia Panta
Choose two or more items and save on your trip:

Santa Ana Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Andean Wings Valley

Andean Wings Valley

4.5 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 4.5-star luxury hotel in Urubamba. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chullpas and Salt Mines of Maras are located nearby.

Vertical Sky Luxury Suites

Vertical Sky Luxury Suites

3 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 3-star lodge in Ollantaytambo. Enjoy free breakfast, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza de Armas and Ollantaytambo Archaeological Site are located nearby.

Jaya Machupicchu Boutique Hotel

Jaya Machupicchu Boutique Hotel

3.5 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 3.5-star spa hotel in Machu Picchu. Enjoy free breakfast, free WiFi, and private hot tubs. Our guests praise the helpful staff in our reviews. Popular attractions Aguas Calientes Hot Springs and Manco Capac Square are located nearby.

NaturaLodge Machu Picchu

NaturaLodge Machu Picchu

3 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 3-star hotel in Machu Picchu. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Aguas Calientes Hot Springs and Manco Capac Square are located nearby.

Sumaq Machu Picchu Hotel

Sumaq Machu Picchu Hotel

4 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 4-star luxury hotel in Machu Picchu. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Aguas Calientes Hot Springs and Manco Capac Square are located nearby.

Wifala Harmony Hotel

Wifala Harmony Hotel

3 out of 5
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Cusco (CUZ)
Stay at this 3-star hotel in Urubamba. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Chullpas and Santuario del Senor de Torrechayoc are located nearby.

Don't see what you're looking for?
See all available trips from Columbus to Santa Ana
View all trips

Top Hotel Deals

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco

3.5 out of 5
Santa Ana, Avenida Abancay 207, Cusco, Cusco
0.03 km from Santa Ana
Stay at this 3.5-star hotel in Cusco. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
Anata Hostel

Anata Hostel

3 out of 5
y pasaje Pasñahuarcuna, Cusco, Cuzco
0.17 km from Santa Ana
Stay at this 3-star hotel in Cusco. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Plaza de Armas and San Pedro Market are located ...
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

5 out of 5
Plazoleta Santo Domingo No 259, Cusco, Cusco
1.29 km from Santa Ana
Stay at this 5-star luxury hotel in Cusco. Enjoy a full-service spa, room service, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Sonesta Hotel Cusco

Sonesta Hotel Cusco

4 out of 5
Ave. El Sol 954, Cusco, Cusco
1.73 km from Santa Ana
Stay at this 4-star business-friendly hotel in Cusco. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff ...
JW Marriott El Convento Cusco

JW Marriott El Convento Cusco

5 out of 5
Esquina De La Calle Ruinas 432, y San Agustin, Cusco, Cusco
1.08 km from Santa Ana
Stay at this 5-star luxury hotel in Cusco. Enjoy free breakfast, a full-service spa, and room service. Our guests praise the helpful staff in our reviews. Popular ...
Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

4 out of 5
Santa Teresa N 344, Cusco, Cusco
0.52 km from Santa Ana
Stay at this 4-star business-friendly hotel in Cusco. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the breakfast and the helpful ...
Antigua Casona San Blas

Antigua Casona San Blas

4 out of 5
Calle Carmen Bajo 243, San Blas, Cusco
1.3 km from Santa Ana
Stay at this 4-star spa hotel in Cusco. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the restaurant in our reviews. ...
Casona Corrales Hotel Boutique

Casona Corrales Hotel Boutique

3.5 out of 5
Sta Teresa, Cusco, Cuzco
0.5 km from Santa Ana
Stay at this 3.5-star spa B&B in Cusco. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Plaza de Armas and San Pedro Market are ...
El Balcon

El Balcon

3 out of 5
Tambo De Montero 222, Cusco, Cusco
0.34 km from Santa Ana
Stay at this 3-star hotel in Cusco. Enjoy free breakfast, room service, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
Wifala Harmony Hotel

Wifala Harmony Hotel

3 out of 5
Sector Querocancha S/N, Urubamba, Cusco
29.77 km from Santa Ana
Stay at this 3-star hotel in Urubamba. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Chullpas and Santuario del Senor de Torrechayoc ...
Novotel Cusco

Novotel Cusco

4 out of 5
San Augustin 239 Esquina, Cusco, Cusco
1.08 km from Santa Ana
Stay at this 4-star historic hotel in Cusco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff ...
Aranwa Cusco Boutique Hotel

Aranwa Cusco Boutique Hotel

4.5 out of 5
San Juan De Dios 255, Cusco, Cusco
0.53 km from Santa Ana
Stay at this 4.5-star luxury hotel in Cusco. Enjoy free breakfast, free WiFi, and an attached winery. Our guests praise the helpful staff in our reviews. Popular ...
Kantu Hotel

Kantu Hotel

3 out of 5
calle chaparro 121, Cusco, Cuzco
0.63 km from Santa Ana
Stay at this 3-star hotel in Cusco. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions San Pedro Market and Plaza de Armas are located ...
Casa Cruz Verde by Peru Garden Hotels

Casa Cruz Verde by Peru Garden Hotels

3 out of 5
336 Cruz Verde, Cusco, Cuzco
0.83 km from Santa Ana
Stay at this 3-star business-friendly hotel in Cusco. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions San Pedro Market and Plaza ...
Ureta Hotel

Ureta Hotel

3.5 out of 5
Barrio Profesional, Calle Lima C12, Cusco
2.25 km from Santa Ana
Stay at this 3.5-star business-friendly hotel in Cusco. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Don't see what you're looking for?
See all available properties in Santa Ana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Sun, Aug 31 - Tue, Sep 9
LIM
Jorge Chavez Intl.
CUZ
Alejandro Velasco Astete Intl.
$66 Roundtrip, found 2 days ago
$66
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Sun, Aug 31 from Jorge Chavez Intl. to Alejandro Velasco Astete Intl., returning Tue, Sep 9, priced at $66 found 2 days ago
Jetsmart SPA
Mon, Sep 1 - Wed, Sep 10
LIM
Jorge Chavez Intl.
CUZ
Alejandro Velasco Astete Intl.
$83 Roundtrip, found 2 days ago
$83
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Mon, Sep 1 from Jorge Chavez Intl. to Alejandro Velasco Astete Intl., returning Wed, Sep 10, priced at $83 found 2 days ago
Delta
Sun, Nov 2 - Sun, Nov 9
LAX
Los Angeles Intl.
CUZ
Alejandro Velasco Astete Intl.
$883 Roundtrip, found 1 day ago
$883
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Nov 2 from Los Angeles Intl. to Alejandro Velasco Astete Intl., returning Sun, Nov 9, priced at $883 found 1 day ago
avianca
Fri, Nov 7 - Wed, Nov 12
LAX
Los Angeles Intl.
CUZ
Alejandro Velasco Astete Intl.
$884 Roundtrip, found 1 day ago
$884
Roundtrip
found 1 day ago
Select avianca flight, departing Fri, Nov 7 from Los Angeles Intl. to Alejandro Velasco Astete Intl., returning Wed, Nov 12, priced at $884 found 1 day ago