James Island Vacation Packages for 2025

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James Island Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

3 out of 5
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this 3-star business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of Charleston Cruise Terminal and Patriots Point are located nearby.

Emeline

Emeline

4 out of 5
Charleston Historic District
Save 100% on your flight
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this 4-star luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the bar in our reviews. Popular attractions Port of Charleston Cruise Terminal and Charleston City Market are located nearby.

The Ryder Hotel

The Ryder Hotel

3.5 out of 5
Charleston Historic District
Save 100% on your flight
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this hotel in Charleston. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Port of Charleston Cruise Terminal and Charleston City Market are located nearby.

The Vendue

The Vendue

4 out of 5
Charleston Historic District
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this 4-star boutique hotel in Charleston. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Port of Charleston Cruise Terminal and Waterfront Park are located nearby.

Hilton Garden Inn Charleston Waterfront/Downtown

Hilton Garden Inn Charleston Waterfront/Downtown

3 out of 5
Downtown Charleston
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this 3-star business-friendly hotel in Charleston. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Port of Charleston Cruise Terminal and Charleston City Market are located nearby.

Elliott House Inn

Elliott House Inn

4 out of 5
Charleston Historic District
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Charleston (CHS)
Stay at this 4-star inn in Charleston. Enjoy free WiFi, room service, and free bicycles on site. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of Charleston Cruise Terminal and Charleston City Market are located nearby.

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Top Hotel Deals

Drury Plaza Hotel North Charleston

Drury Plaza Hotel North Charleston

3 out of 5
West Montague Avenue, 2934, North Charleston, SC
14.14 km from city center
Stay at this 3-star business-friendly hotel in North Charleston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Charleston Tanger Outlets ...
Hyatt Place North Charleston

Hyatt Place North Charleston

3 out of 5
2455 Prospect Drive, North Charleston, SC
21.81 km from city center
Stay at this 3-star business-friendly hotel in North Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
The Francis Marion Hotel

The Francis Marion Hotel

4 out of 5
387 King St, Charleston, SC
3.95 km from city center
Book a stay at this spa hotel in Charleston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
Emeline

Emeline

4 out of 5
181 Church St, Charleston, SC
3.8 km from city center
Stay at this 4-star luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the bar in ...
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

3 out of 5
1472 Highway 17 North, Mount Pleasant, SC
12.27 km from city center
Stay at this 3-star business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
La Quinta Inn & Suites by Wyndham Charleston Riverview

La Quinta Inn & Suites by Wyndham Charleston Riverview

3 out of 5
11 Ashley Point Drive, Charleston, SC
2.71 km from city center
Stay at this 3-star business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the convenient parking and ...
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

4 out of 5
20 Patriots Point Rd, Mount Pleasant, SC
6 km from city center
Book a stay at this beach resort in Mount Pleasant. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the bar in our reviews. ...
The Ryder Hotel

The Ryder Hotel

3.5 out of 5
237 Meeting Street, Charleston, SC
3.81 km from city center
Stay at this hotel in Charleston. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the helpful staff in ...
Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

3.5 out of 5
560 King Street, Charleston, SC
4.51 km from city center
Stay at this 3.5-star business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
The Charleston Place

The Charleston Place

5 out of 5
205 Meeting Street, Charleston, SC
3.66 km from city center
Book a stay at this spa hotel in Charleston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
Tides Folly Beach, Charleston's Oceanfront Hotel

Tides Folly Beach, Charleston's Oceanfront Hotel

3 out of 5
1 Center Street Highway 171, Folly Beach, SC
11.01 km from city center
Book a stay at this beach hotel in Folly Beach. Enjoy 2 restaurants, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff ...
Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG

Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG

2.5 out of 5
250 Spring Street, Charleston, SC
3.69 km from city center
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
West Ashley Inn

West Ashley Inn

2 out of 5
2058 Savannah Hwy, Charleston, SC
8.38 km from city center
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Mills House Charleston, Curio Collection by Hilton

Mills House Charleston, Curio Collection by Hilton

4 out of 5
115 Meeting Street, Charleston, SC
3.37 km from city center
Stay at this 4-star business-friendly hotel in Charleston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful ...
Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG

3.5 out of 5
250 Johnnie Dodds Blvd, Hwy 17, Mount Pleasant, SC
7.63 km from city center
Stay at this 3.5-star business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the ...
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See all available properties in James Island
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Jun 17 - Tue, Jun 24
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$147 Roundtrip, found 3 days ago
$147
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Jun 17 from John F. Kennedy Intl. to Charleston Intl., returning Tue, Jun 24, priced at $147 found 3 days ago
Frontier Airlines
Thu, Sep 4 - Thu, Sep 11
PHL
Philadelphia Intl.
CHS
Charleston Intl.
$175 Roundtrip, found 2 days ago
$175
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Philadelphia Intl. to Charleston Intl., returning Thu, Sep 11, priced at $175 found 2 days ago
Breeze Airways
Fri, Aug 22 - Mon, Aug 25
SWF
Stewart Intl.
CHS
Charleston Intl.
$184 Roundtrip, found 15 hours ago
$184
Roundtrip
found 15 hours ago
Select Breeze Airways flight, departing Fri, Aug 22 from Stewart Intl. to Charleston Intl., returning Mon, Aug 25, priced at $184 found 15 hours ago
Spirit Airlines
Wed, Jul 16 - Mon, Jul 21
DFW
Dallas-Fort Worth Intl.
CHS
Charleston Intl.
$195 Roundtrip, found 4 days ago
$195
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Wed, Jul 16 from Dallas-Fort Worth Intl. to Charleston Intl., returning Mon, Jul 21, priced at $195 found 4 days ago