Downtown Des Moines Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Top Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
0.47 km from Downtown Des Moines
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Surety Hotel

Surety Hotel

4 out of 5
206 6th Ave., Des Moines, IA
0.2 km from Downtown Des Moines
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar in our reviews. ...
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St, Des Moines, IA
0.24 km from Downtown Des Moines
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

2.5 out of 5
929 3rd St, Des Moines, IA
0.87 km from Downtown Des Moines
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave, Des Moines, IA
1.1 km from Downtown Des Moines
Stay at this 3-star hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. ...
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

3 out of 5
418 6th Avenue, Des Moines, IA
0.09 km from Downtown Des Moines
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St, Des Moines, IA
0.8 km from Downtown Des Moines
Stay at this 3.5-star hotel in Des Moines. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
435 Park Street, Des Moines, IA
0.45 km from Downtown Des Moines
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

2.5 out of 5
120 Sw Water St, Des Moines, IA
0.7 km from Downtown Des Moines
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

2.5 out of 5
333 SW 11th St, Des Moines, IA
0.88 km from Downtown Des Moines
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

3 out of 5
201 E. Locust Street, Des Moines, IA
0.89 km from Downtown Des Moines
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel

3.5 out of 5
401 Locust St, Des Moines, IA
0.17 km from Downtown Des Moines
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
Des Moines Marriott Downtown

Des Moines Marriott Downtown

3.5 out of 5
700 Grand Ave, Des Moines, IA
0.15 km from Downtown Des Moines
Book a stay at this business-friendly hotel in Des Moines. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful ...
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

2.5 out of 5
207 Crocker Street, Des Moines, IA
0.74 km from Downtown Des Moines
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown

3 out of 5
100 SW Water Street, Des Moines, IA
0.65 km from Downtown Des Moines
Stay at this 3-star hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Mon, Jun 23 - Fri, Jun 27
DEN
Denver Intl.
DSM
Des Moines Intl.
$164 Roundtrip, found 4 days ago
$164
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Jun 23 from Denver Intl. to Des Moines Intl., returning Fri, Jun 27, priced at $164 found 4 days ago
Delta
Tue, Jul 8 - Wed, Jul 16
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$237 Roundtrip, found 5 days ago
$237
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jul 8 from Sky Harbor Intl. to Des Moines Intl., returning Wed, Jul 16, priced at $237 found 5 days ago
Delta
Tue, Jul 29 - Wed, Aug 6
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jul 29 from Newark Liberty Intl. Airport to Des Moines Intl., returning Wed, Aug 6, priced at $259 found 6 days ago
United
Mon, Oct 27 - Tue, Oct 28
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$424 Roundtrip, found 16 hours ago
$424
Roundtrip
found 16 hours ago
Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $424 found 16 hours ago