
Cheap 2025 Medical Center District Hotels
Photo by Linda Cronan
Choose from 4548 Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd, San Antonio, TX
2.3 km from Medical Center District
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
2.88 km from Medical Center District
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...

Fairfield Inn & Suites by Marriott San Antonio Medical Center
7203 Wurzbach Road, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
0.97 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Riverwalk Plaza
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.3 km from Medical Center District
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.29 km from Medical Center District
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...

Crockett Hotel
320 Bonham, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.65 km from Medical Center District
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...

Spark By Hilton San Antonio Northwest near Six Flags
6755 North Loop 1604 West, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
10.13 km from Medical Center District
Stay at this 3-star hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the clean rooms in our reviews. Popular attractions ...

La Cantera Resort & Spa
16641 La Cantera Pkwy, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
11.32 km from Medical Center District
Stay at this 4-star spa hotel in San Antonio. Enjoy 5 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff ...

Menger Hotel
204 Alamo Plaza, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.59 km from Medical Center District
Stay at this 3.5-star historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our ...

JW Marriott San Antonio Hill Country Resort & Spa
23808 Resort Pkwy, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
24.29 km from Medical Center District
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy 4 outdoor pools, a full-service spa, and 6 restaurants. Our guests praise the helpful staff and the ...

Omni La Mansion del Rio
112 College St, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.28 km from Medical Center District
Stay at this 4-star spa hotel in San Antonio. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...

Kimpton Santo San Antonio - Riverwalk by IHG
431 South Alamo Street, San Antonio, TX
Free Cancellation
12.85 km from Medical Center District
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Popular attractions River Walk and San Antonio River ...

InterContinental San Antonio Riverwalk by IHG
111 East Pecan Street, San Antonio, TX
Free Cancellation
11.83 km from Medical Center District
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Popular attractions San Antonio River and Alamo ...

The Westin San Antonio North
9821 Colonnade Blvd, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
3.43 km from Medical Center District
Book a stay at this business-friendly hotel in San Antonio. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...

La Quinta Inn & Suites by Wyndham San Antonio Downtown
100 W. Cesar Chavez Blvd, San Antonio, TX
12.34 km from Medical Center District
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Hotel Valencia Riverwalk
150 E Houston St, San Antonio, TX
Free Cancellation
Reserve now, pay when you stay
12.1 km from Medical Center District
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Medical Center District, San Antonio Hotel Guide
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More Medical Center District Hotel Deals for Seniors and Members
- La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
- San Antonio Marriott Northwest Medical Center
- Fairfield Inn & Suites by Marriott San Antonio Medical Center
- Riverwalk Plaza
- Drury Plaza Hotel San Antonio Riverwalk
- Crockett Hotel
- Spark By Hilton San Antonio Northwest near Six Flags
- La Cantera Resort & Spa
- Menger Hotel
- JW Marriott San Antonio Hill Country Resort & Spa