Vacation Packages to Los Santos for 2025
Los Santos Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort
Price was $1,164, price is now $895 per person
$895
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Stay at this 4-star golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Centenario Bridge and Summit Botanical Gardens & Zoo are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,408, price is now $1,374 per person
$1,374
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,377, price is now $974 per person
$974
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Bristol Panama, a Registry Collection Hotel
Bella Vista
Price was $1,732, price is now $1,264 per person
$1,264
per person
Oct 18 - Oct 25
found 9 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
MARINN PLACE Financial District
Bella Vista
Price was $1,387, price is now $1,053 per person
$1,053
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Hotel La Compania, in the Unbound Collection by Hyatt
Casco Viejo
Price was $1,999, price is now $1,540 per person
$1,540
per person
Oct 18 - Oct 25
found 15 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Panama City (PTY)
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Top Hotel Deals
Villa Marina Lodge & Condos
Playa Venao, Las Escobas del Venado, Los Santos
39.28 km from city center
Stay at this 3.5-star beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...
Playa Venao Hotel Resort
Playa Venao, Las Escobas del Venado, Los Santos
38.38 km from city center
Stay at this 3.5-star beach resort in Las Escobas del Venado. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located ...
Selina River Venao
Belisario Porras Avenue, Playa Venao, Las Escobas del Venado, Provincia de Herrera
38.2 km from city center
Stay at this 3-star hotel in Las Escobas del Venado. Enjoy free parking, breakfast (surcharge), and daily housekeeping. Popular attraction Venao Beach is located ...
Hotel Presidente
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
0.13 km from city center
Stay at this 3.5-star hotel in Las Tablas. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Belisario Porras Park and Museo Belisario ...
Hotel Punta Franca
Camino a Puerto Escondido, Los Destiladeros, Punta Mala, Los Santos
42.37 km from city center
Stay at this 3-star beach hotel in Punta Mala. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Puerto Escondido Beach and ShokoGi Panama ...
Hotel Posada Destiladeros
Calle principal Los Destiladeros, Los Destiladeros Pedasi, Punta Mala, Provincia de los Santos
42.74 km from city center
Stay at this 3-star beach lodge in Punta Mala. Enjoy free breakfast, free parking, and a beach locale. Popular attractions ShokoGi Panama and Los Destiladeros ...
Casa Lajagua
Calle principal de Pedasi, Pedasí, Panama
37.77 km from city center
Stay at this 3-star B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
Alaya Yoga & Surf & Retreat
Venao, Canas, Los Santos
35.98 km from city center
Stay at this 4-star spa hotel in Canas. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located nearby.
Hotel Riu Playa Blanca - All Inclusive
Finca 43.668, Rio Hato, Cocle
67.98 km from city center
Stay at this 3.5-star beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Grand Decameron Panama, A Trademark All Inclusive Resort
Avenida Principal Farallon Kilometro 115, Carretera Interamericana - Penonome, Rio Hato, Cocle
68.41 km from city center
Stay at this 3.5-star beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón ...
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
340 Calle 3ra Buenaventura, Buenaventura Beach Community, El Chiru, Cocle
64.63 km from city center
Stay at this 5-star luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
Playa Blanca Beach Resort - All Inclusive
115 Km Via Interamericana, Rio Hato, Cocle
66.58 km from city center
Stay at this 4-star beach property in Rio Hato. Enjoy free breakfast, free parking, and 3 outdoor pools. Our guests praise the property condition in our reviews. ...
Hotel Faranda Guayacanes, a member of Radisson Individuals
Via Circunvalacion S/n, Chitre, Herrera
28.03 km from city center
Stay at this 3-star family-friendly hotel in Chitre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.