Vacation Packages to Los Santos for 2026
Los Santos Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
$1,043
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
My experience was wonderful. The staff was pleasant, breakfast had a lot of options. I have already recommended people to stay at rui plaza
Reviewed on Oct 20, 2026
Megapolis Hotel Panamá
San Francisco
$1,487
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,446
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Property was clean and nice, breakfast was excellent.
Reviewed on Oct 20, 2026
Riande Aeropuerto Hotel & Casino
Tocumen Airport
$1,063
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
W Panama
Bella Vista
$1,225
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Hyatt Regency Panama City
Bella Vista
$1,233
per person
Dec 6 - Dec 13
found 23 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Top Hotel Deals
Villa Marina Hotel
Playa Venao Las Escobas del Venado Los Santos
Book a stay at this family-friendly hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in ...
Selina Venao Beach East
Playa Venao 1 Las Escobas del Venado Los Santos
Book a stay at this beach hostel in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Popular attraction Venao Beach is located ...
Hotel Punta Franca
Camino a Puerto Escondido Punta Mala Los Santos
Stay at this hotel in Punta Mala. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Puerto Escondido Beach and Los Destiladeros Beach are ...
WAO Beach Hotel
Playa Venao Las Escobas del Venado Los Santos Province
Book a stay at this beach hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and 3 restaurants. Popular attraction Venao Beach is located ...
Playa Venao Hotel Resort
Playa Venao Las Escobas del Venado Los Santos
Book a stay at this beach resort in Las Escobas del Venado. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located ...
Hotel Presidente
Calle Moises Espino Las Tablas
Stay at this hotel in Las Tablas. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Belisario Porras Park and Museo Belisario Porras ...
Casa Lajagua
Calle principal de Pedasi Pedasí Panama
Stay at this B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
Selina Venao Beach West
Belisario Porras Avenue Las Escobas del Venado Provincia de Herrera
Stay at this hotel in Las Escobas del Venado. Enjoy free parking, breakfast (surcharge), and a business center. Popular attraction Venao Beach is located ...
Sansara Surf and Yoga Resort - Retreat
Calle Principal Cambutal Los Santos
Book a stay at this luxury resort in Cambutal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Los Buzos Beach and Guanico Abajo Beach ...
Pedasi Sport Club
Calle Principal Pedasí Los Santos
Stay at this hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located nearby.
Casa Loma
Via Principal Pedasí
Stay at this hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located nearby.
Alaya Panama – Private Retreat & Wellness Resort
Venao Canas Los Santos
Stay at this hotel in Canas. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Venao Beach is located nearby.
La Placita - Apartamentos
Agustin Cano Castillero Las Tablas Provincia de Los Santos
Stay at this apartment in Las Tablas. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located nearby.
Casa Magna Panama
Agustin Cano Castillero Las Tablas Provincia de Los Santos
Stay at this hostel in Las Tablas. Enjoy free parking, a garden, and housekeeping. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located ...
Pocri Country Resort
El Llano, Calle Villa Del Carmen Pocrí Provincia de Los Santos
Stay at this hotel in Pocrí. Enjoy free breakfast, free WiFi, and free parking.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular vacation package destinations in Los Santos
- Las Escobas del Venado Vacations
- Pedasí Vacations
- Las Tablas Vacations
- Cambutal Vacations
- Canas Vacations
- Punta Mala Vacations
- Guarare Vacations
- La Villa de los Santos Vacations
- Pocrí Vacations
- Tonosi Vacations
- Guanico Abajo Vacations
- Santo Domingo Vacations
- Isla Iguana Vacations
- Bucaro Vacations
- La Palma Vacations