Vacation Packages to Los Santos for 2026
Los Santos Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Save 100% on your flight
Price was $1,449, price is now $931 per person
$931
per person
Aug 3 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was $1,776, price is now $1,032 per person
$1,032
per person
Aug 3 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,342, price is now $1,470 per person
$1,470
per person
Jul 25 - Jul 31
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,360, price is now $945 per person
$945
per person
Aug 3 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino
Price was $1,580, price is now $1,101 per person
$1,101
per person
Jul 25 - Jul 31
found 22 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Save 100% on your flight
Price was $2,368, price is now $1,771 per person
$1,771
per person
Aug 3 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Top Hotel Deals
Villa Marina Hotel
Playa Venao Las Escobas del Venado Los Santos
39.28 km from city center
Book a stay at this beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...
Selina River Venao
Belisario Porras Avenue Las Escobas del Venado Provincia de Herrera
38.34 km from city center
Stay at this hotel in Las Escobas del Venado. Enjoy free parking, breakfast (surcharge), and daily housekeeping. Popular attraction Venao Beach is located ...
Selina Playa Venao - Hostel
Playa Venao 1 Las Escobas del Venado Los Santos
38.7 km from city center
Book a stay at this beach hostel in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Popular attraction Venao Beach is located ...
Hotel Playa Cambutal
Calle Principal, Cambutal-Tonosi Cambutal Los Santos
62.27 km from city center
Book a stay at this beach hotel in Cambutal. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Los Buzos Beach and Guanico Abajo Beach are ...
Casa Magna Panama
Agustin Cano Castillero Las Tablas Provincia de Los Santos
0.46 km from city center
Stay at this hostel in Las Tablas. Enjoy free parking, a garden, and housekeeping. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located ...
Hotel Presidente
Calle Moises Espino Las Tablas
0.13 km from city center
Stay at this hotel in Las Tablas. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Belisario Porras Park and Museo Belisario Porras ...
Playa Venao Hotel Resort
Playa Venao Las Escobas del Venado Los Santos
38.38 km from city center
Book a stay at this beach resort in Las Escobas del Venado. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located ...
Casa Lajagua
Calle principal de Pedasi Pedasí Panama
37.77 km from city center
Stay at this B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
Hotel Punta Franca
Camino a Puerto Escondido Punta Mala Los Santos
42.37 km from city center
Book a stay at this beach hotel in Punta Mala. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Puerto Escondido Beach and ShokoGi Panama ...
WAO Beach Hotel
Playa Venao Las Escobas del Venado Los Santos Province
38.64 km from city center
Book a stay at this beach hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and 3 restaurants. Popular attraction Venao Beach is located ...
Hotel El Sitio Playa Venao
Playa Venao Las Escobas del Venado Los Santos
38.37 km from city center
Book a stay at this beach hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Popular attraction Venao Beach is located ...
Sansara Surf and Yoga Resort - Retreat
Calle Principal Cambutal Los Santos
62.76 km from city center
Book a stay at this luxury resort in Cambutal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Los Buzos Beach and Guanico Abajo Beach ...
Casa Loma
Via Principal Pedasí
37.76 km from city center
Stay at this hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.