Vacation Packages to Panama for 2026

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Panama Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel
3.5-star property

MARINN Tropical Vibes Hotel

Amador

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$902
per person
found 1 day ago
Stay at this hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Good

Reviewed on Oct 10, 2026

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

San Francisco

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
$1,245
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

Casco Viejo

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
$1,333
per person
found 1 day ago
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Very well center from casco viejo and everything to walk the property is in good condition and well maintained. Breakfast is very good, the bed and A/C are good. The only thing is the cleaning staff need more training on tightening the room.

Reviewed on Oct 23, 2026

Riande Aeropuerto Hotel & Casino
4.0-star property

Riande Aeropuerto Hotel & Casino

Tocumen Airport

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$985
per person
found 1 day ago
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Wish they had coffee pots in the rooms or at least had coffee ready earlier in the mornings especially for those that have to catch a 4:00am shuttle to the airport.

Reviewed on Oct 23, 2026

Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

Bella Vista

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,000
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Me gusta la ubica o, muy conveniente. El personal muy atento. El desayuno espectacular

Reviewed on Oct 23, 2026

Hyatt Regency Panama City
5.0-star property

Hyatt Regency Panama City

Bella Vista

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,104
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Las Clementinas
3.5-star property

Las Clementinas

Casco Viejo

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,183
per person
found 1 day ago
Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Casa Panamá
4.0-star property

Hotel Casa Panamá

Casco Viejo

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$928
per person
found 1 day ago
Stay at this hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Americas Golden Tower Panama
4.0-star property

Las Americas Golden Tower Panama

San Francisco

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,054
per person
found 1 day ago
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Clean Room

Reviewed on Oct 21, 2026

Sheraton Grand Panama
4.0-star property

Sheraton Grand Panama

San Francisco

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,075
per person
found 1 day ago
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.
Renaissance Panama City Hotel
5.0-star property

Renaissance Panama City Hotel

Bella Vista

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$983
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and breakfast (surcharge). Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
The property needs to be updated

Reviewed on Oct 21, 2026

JW Marriott Panama
5.0-star property

JW Marriott Panama

San Francisco

Dec 2 - Dec 7

5 night stay

Baltimore (BWI) to Panama City (PTY)

American Airlines • Non-stop roundtrip • Coach
$1,578
per person
found 1 day ago
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Inodoros dañados, ducha dañada se veía outdated. No hubo mucha atención del personal. No volvería y demasiado caro para lo que ofrecen.

Reviewed on Oct 23, 2026

Don't see what you're looking for?
See all available trips from Columbus to Panama
View all trips

Search vacation deals in Panama's top destinations

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City

Panama City
A waterfront area with buildings, boats, and a dock.

Bocas del Toro

Bocas del Toro
A beach with waves, a boat in the distance, and a forested hillside.

Rio Hato

Rio Hato
A park with a large rock, a winding path, and a hill in the background.

Boquete

Boquete
A group of women in white dresses with lace details, dancing outdoors.

Veracruz

Veracruz
A historic stone fortress with a central dome and surrounding walls.

Colon

Colon
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Tocumen

Tocumen
A mountainous landscape with scattered houses and a valley.

El Valle de Anton

El Valle de Anton
A staircase leading to a building with a yellow facade, surrounded by greenery and a large stone statue.

Bastimentos

Bastimentos

Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
147.07 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
146.51 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
164.19 km from city center
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
147.27 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama
137.86 km from city center
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Via Israel y Calle 71, San Francisco Panama City Panama
148.72 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
79.88 km from city center
Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
Principe Hotel and Suites

Principe Hotel and Suites

Via Argentina Panama City Panama
146.97 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Avenida Peru Y Calle 30 Panama City Panama Province
144.84 km from city center
Stay at this hotel in Panama City. Enjoy free breakfast, a 24-hour front desk, and 4 meeting rooms. Popular attractions Albrook Shopping Mall and Cinta Costera ...
The Executive Hotel

The Executive Hotel

Calle 52 Panama City Panama
146.6 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Don't see what you're looking for?
See all available properties in Panama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, Oct 29 - Fri, Oct 30
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264
Roundtrip
found 5 days ago
Select Copa flight, departing Thu, Oct 29 from Juan Santamaría Intl. to Tocumen Intl., returning Fri, Oct 30, priced at $264 found 5 days ago
avianca
United
Sat, Jan 16 - Thu, Jan 21
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$557
Roundtrip
found 2 hours ago
Select United flight, departing Sat, Jan 16 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Thu, Jan 21, priced at $557 found 2 hours ago
American Airlines
Delta