Santo Domingo Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Santo Domingo Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Save 100% on your flight
Price was $1,239, price is now $762 per person
$762
per person
Aug 28 - Sep 4
found 1 day ago
Roundtrip flight included
Belize City (BZE) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,177, price is now $1,152 per person
$1,152
per person
Aug 28 - Sep 4
found 1 day ago
Roundtrip flight included
Belize City (BZE) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was $1,642, price is now $897 per person
$897
per person
Aug 28 - Sep 4
found 1 day ago
Roundtrip flight included
Belize City (BZE) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama
San Francisco
Save 100% on your flight
Price was $1,225, price is now $810 per person
$810
per person
Aug 28 - Sep 4
found 1 day ago
Roundtrip flight included
Belize City (BZE) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino
Price was $1,580, price is now $1,101 per person
$1,101
per person
Jul 25 - Jul 31
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Save 100% on your flight
Price was $1,953, price is now $1,386 per person
$1,386
per person
Aug 28 - Sep 4
found 1 day ago
Roundtrip flight included
Belize City (BZE) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to Santo Domingo
View all tripsTop Hotel Deals
Hotel Faranda Guayacanes, a member of Radisson Individuals
Via Circunvalacion S/n Chitre Herrera
34.41 km from city center
Book a stay at this family-friendly hotel in Chitre. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Casa Magna Panama
Agustin Cano Castillero Las Tablas Provincia de Los Santos
7.22 km from city center
Stay at this hostel in Las Tablas. Enjoy free parking, a garden, and housekeeping. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located ...
Hotel Presidente
Calle Moises Espino Las Tablas
7.1 km from city center
Stay at this hotel in Las Tablas. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Belisario Porras Park and Museo Belisario Porras ...
Casa Lajagua
Calle principal de Pedasi Pedasí Panama
31.33 km from city center
Stay at this B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
Casa Loma
Via Principal Pedasí
31.32 km from city center
Stay at this hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located nearby.
Alaya Yoga & Surf & Retreat
Venao Canas Los Santos
33.86 km from city center
Stay at this hotel in Canas. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Venao Beach is located nearby.
Pedasi Sport Club
Calle Principal Pedasí Los Santos
31.31 km from city center
Stay at this hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located nearby.
Pocri Country Resort
El Llano, Calle Villa Del Carmen Pocrí Provincia de Los Santos
13.92 km from city center
Stay at this hotel in Pocrí. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Isla de Cañas is located nearby.
Hostal Casa de Quincha
Residencial Los Días Las Tablas Provincia de Los Santos
7.53 km from city center
Stay at this hostel in Las Tablas. Enjoy a garden and housekeeping. Popular attractions Belisario Porras Park and Iglesia Santa Librada are located nearby.
Baruch Tropical Ranch
Vía La Concepción hacia playa La Yeguada Pocrí Los Santos
15.75 km from city center
Stay at this B&B in Pocrí. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Isla de Cañas is located nearby.
La Placita - Apartamentos
Agustin Cano Castillero Las Tablas Provincia de Los Santos
7.23 km from city center
Stay at this apartment in Las Tablas. Popular attractions Museo Belisario Porras and Iglesia Santa Librada are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.