Vacation Packages to Los Santos for 2025

Choose two or more items and save on your trip:

Top Hotel Deals

Villa Marina Lodge & Condos

Villa Marina Lodge & Condos

3.5 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
39.28 km from city center
Stay at this 3.5-star beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...
Hotel Presidente

Hotel Presidente

3.5 out of 5
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
0.13 km from city center
Stay at this 3.5-star hotel in Las Tablas. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Belisario Porras Park and Museo Belisario ...
Casa Lajagua

Casa Lajagua

3 out of 5
Calle principal de Pedasi, Pedasí, Panama
37.77 km from city center
Stay at this 3-star B&B in Pedasí. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Playa El Arenal and Playa El Toro are located ...
Hotel El Sitio Playa Venao

Hotel El Sitio Playa Venao

3 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
38.38 km from city center
Stay at this 3-star beach hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Popular attraction Venao Beach is located ...
Playa Venao Hotel Resort

Playa Venao Hotel Resort

3.5 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
38.38 km from city center
Stay at this 3.5-star beach resort in Las Escobas del Venado. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located ...
Hotel Punta Franca

Hotel Punta Franca

3 out of 5
Camino a Puerto Escondido, Los Destiladeros, Punta Mala, Los Santos
42.37 km from city center
Stay at this 3-star beach hotel in Punta Mala. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Puerto Escondido Beach and ShokoGi Panama ...
Hotel Posada Destiladeros

Hotel Posada Destiladeros

3 out of 5
Calle principal Los Destiladeros, Los Destiladeros Pedasi, Punta Mala, Provincia de los Santos
42.74 km from city center
Stay at this 3-star beach lodge in Punta Mala. Enjoy free breakfast, free parking, and a beach locale. Popular attractions ShokoGi Panama and Los Destiladeros ...
Alaya Yoga & Surf & Retreat

Alaya Yoga & Surf & Retreat

4 out of 5
Venao, Canas, Los Santos
35.98 km from city center
Stay at this 4-star spa hotel in Canas. Enjoy free WiFi, free parking, and a full-service spa. Popular attraction Venao Beach is located nearby.
Casa Loma

Casa Loma

3 out of 5
Via Principal, across from Banco National, Pedasí
37.76 km from city center
Stay at this 3-star hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located ...
Pocri Country Resort

Pocri Country Resort

3 out of 5
El Llano, Calle Villa Del Carmen, Pocrí, Provincia de Los Santos
20.72 km from city center
Stay at this 3-star hotel in Pocrí. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Isla de Cañas is located nearby.
Pedasi Sport Club

Pedasi Sport Club

3 out of 5
Calle Principal, ef frente Policia Nacional, Pedasí, Los Santos
37.75 km from city center
Stay at this 3-star hotel in Pedasí. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa El Arenal and Playa El Toro are located ...
Hostel Villas De Zianit

Hostel Villas De Zianit

Calle Jobo, Casa 97, Guarare, Los Santos Province
5.03 km from city center
Stay at this hostel in Guarare. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Museo Manuel F Zárate and Academy of Customs & ...
Sansara Surf and Yoga Resort - Retreat

Sansara Surf and Yoga Resort - Retreat

4.5 out of 5
Calle Principal, Cambutal, Los Santos
62.74 km from city center
Stay at this 4.5-star luxury resort in Cambutal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Los Buzos Beach and Guanico Abajo Beach ...
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668, Rio Hato, Cocle
67.98 km from city center
Stay at this 3.5-star beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon. Kilometro 11, Carretera Interamericana - Penonome, Rio Hato, Cocle
68.39 km from city center
Stay at this 3.5-star beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón ...
Don't see what you're looking for?
See all available properties in Los Santos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.