Downtown Isle of Palms Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Photo by ‎Alex Cadle
Choose two or more items and save on your trip:

Top Hotel Deals

The Palms Oceanfront Hotel

The Palms Oceanfront Hotel

3.5 out of 5
1126 Ocean Blvd, Isle of Palms, SC
0.1 km from Downtown Isle of Palms
Stay at this 3.5-star beach hotel in Isle of Palms. Enjoy a beach locale, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and ...
Seaside Inn Oceanfront

Seaside Inn Oceanfront

2.5 out of 5
1004 Ocean Blvd, Isle of Palms, SC
0.27 km from Downtown Isle of Palms
Book a stay at this beach hotel in Isle of Palms. Enjoy free WiFi, a beach locale, and parking (surcharge). Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG

Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG

2.5 out of 5
250 Spring Street, Charleston, SC
15.66 km from Downtown Isle of Palms
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
The Francis Marion Hotel

The Francis Marion Hotel

4 out of 5
387 King St, Charleston, SC
13.87 km from Downtown Isle of Palms
Book a stay at this spa hotel in Charleston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG

3.5 out of 5
250 Johnnie Dodds Boulevard, Mount Pleasant, SC
10.33 km from Downtown Isle of Palms
Stay at this 3.5-star business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the ...
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

3 out of 5
1472 Highway 17 North, Mount Pleasant, SC
6.38 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
Drury Plaza Hotel North Charleston

Drury Plaza Hotel North Charleston

3 out of 5
West Montague Avenue, 2934, North Charleston, SC
23.02 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in North Charleston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions North Charleston Coliseum ...
Emeline

Emeline

4 out of 5
181 Church St, Charleston, SC
13.24 km from Downtown Isle of Palms
Stay at this 4-star luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the bar in ...
Courtyard by Marriott Charleston-North Charleston

Courtyard by Marriott Charleston-North Charleston

3 out of 5
7465 NORTHSIDE DR, North Charleston, SC
29.76 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in North Charleston. Enjoy breakfast (surcharge), a health club, and parking (surcharge). Our guests praise the helpful ...
SpringHill Suites by Marriott Charleston N./Ashley Phosphate

SpringHill Suites by Marriott Charleston N./Ashley Phosphate

3 out of 5
7535 N Forest Drive, North Charleston, SC
29.78 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in North Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Charleston Riverview by IHG

Holiday Inn Charleston Riverview by IHG

3 out of 5
301 Savannah Hwy, Charleston, SC
16.58 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in Charleston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the bar in ...
The Vendue

The Vendue

4 out of 5
19 Vendue Range, Charleston, SC
12.93 km from Downtown Isle of Palms
Stay at this 4-star boutique hotel in Charleston. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff in our ...
The Charleston Place

The Charleston Place

5 out of 5
130 Market St, Charleston, SC
13.44 km from Downtown Isle of Palms
Book a stay at this spa hotel in Charleston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
La Quinta Inn & Suites by Wyndham Charleston Riverview

La Quinta Inn & Suites by Wyndham Charleston Riverview

3 out of 5
11 Ashley Point Drive, Charleston, SC
16.39 km from Downtown Isle of Palms
Stay at this 3-star business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the convenient parking and ...
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

4.5 out of 5
28 Patriots Point Road, Mount Pleasant, SC
10.98 km from Downtown Isle of Palms
Stay at this 4.5-star luxury resort in Mount Pleasant. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful ...
Don't see what you're looking for?
See all available properties in Downtown Isle of Palms
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Fri, Dec 12 - Sat, Dec 13
EWR
Newark Liberty Intl. Airport
CHS
Charleston Intl.
$65 Roundtrip, found 1 day ago
$65
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Fri, Dec 12 from Newark Liberty Intl. Airport to Charleston Intl., returning Sat, Dec 13, priced at $65 found 1 day ago
Delta
Fri, Dec 12 - Sat, Dec 13
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$127 Roundtrip, found 1 day ago
$127
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Dec 12 from John F. Kennedy Intl. to Charleston Intl., returning Sat, Dec 13, priced at $127 found 1 day ago
United
Fri, Dec 12 - Sat, Dec 13
EWR
Newark Liberty Intl. Airport
CHS
Charleston Intl.
$127 Roundtrip, found 1 day ago
$127
Roundtrip
found 1 day ago
Select United flight, departing Fri, Dec 12 from Newark Liberty Intl. Airport to Charleston Intl., returning Sat, Dec 13, priced at $127 found 1 day ago
JetBlue Airways
Fri, Dec 12 - Sat, Dec 13
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$142 Roundtrip, found 1 day ago
$142
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Fri, Dec 12 from John F. Kennedy Intl. to Charleston Intl., returning Sat, Dec 13, priced at $142 found 1 day ago
American Airlines
Fri, Dec 12 - Sat, Dec 13
LGA
LaGuardia
CHS
Charleston Intl.
$152 Roundtrip, found 1 day ago
$152
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 12 from LaGuardia to Charleston Intl., returning Sat, Dec 13, priced at $152 found 1 day ago