A tropical island with palm trees and a clear blue sky.

Luxury Hotels in Panama

Top Cities in Panama

A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.
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Panama City

Panama City

Check availability on Panama Luxury Hotels

Our top choices for Panama luxury hotels

A poolside area with lounge chairs and a view of the ocean.

1. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
JW Marriott Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

2. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Art deco elegance meets modern luxury in this Panama City hotel featuring 2 bars, a full-service spa, and an outdoor pool.
Bristol Panama, a Registry Collection Hotel
A rooftop pool area with modern seating and a view of the city skyline at dusk.

3. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
Waldorf Astoria Panama
A white building with multiple balconies, large windows, and decorative railings.

4. American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (828 reviews)
  • cleanliness
    A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalized service in a historic district.
American Trade Hotel
A nighttime cityscape with a modern building featuring a glass facade and illuminated interior.

5. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Indulge in Panama City luxury with an outdoor pool, full-service spa, and casino at this stylish hotel near Via Espana.
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

6. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
Hilton Panama
Bar (on property)

7. Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,000 reviews)
  • cleanliness
    Indulgent pampering awaits at this Beaux Arts Panama City gem with spa, casino, and rooftop bar.
Megapolis Hotel Panamá
A beachside lounge with wicker furniture, a wooden walkway, and palm trees.

8. The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection
5.0 star property
El Chiru
9.2 out of 10, Wonderful, (789 reviews)
  • cleanliness
    Immerse in beachfront opulence with 12 stunning pools, a full-service spa, and private beach access at this Panama golf resort.
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

9. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,140 reviews)
  • cleanliness
    Panama City hotel offers upscale comfort with spa, indoor pool, and pillowtop beds in San Francisco district.
Las Americas Golden Tower Panama
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.

10. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Luxury redefined in Panama City with rooftop pool, premium dining, and concierge services to elevate your urban escape.
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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