Resorts & Hotels with Spas in Panama

Check availability on Panama Resorts & Hotels with Spas

Pick from 268 Panama Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Meeting facility

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (959)
"Very clean and upscale!"
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2116)
"Great place to stay"
Crowne Plaza Panama Airport by IHG
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (581)
"Beautiful hotel with great service and ambiance. "
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Marriott Panama Hotel
Terrace/patio

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Rooms were very spacious and clean. Breakfast was buffet style and great"
Marriott Panama Hotel
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1000)
"Super nice hotel with spa. "
Bristol Panama, a Registry Collection Hotel
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View | In-room safe, blackout drapes, iron/ironing board

W Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"Everything was good. It was a great stay! "
W Panama
Radisson Colon 2,000 Hotel & Casino
Outdoor pool, open 6 AM to 8 PM, sun loungers

Radisson Colon 2,000 Hotel & Casino

4.0 star property
8.0 out of 10, Very Good, (754)
"Best Hotel In The Area"
Radisson Colon 2,000 Hotel & Casino
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (461)
"Beautiful room staff was very helpful. Great hotel."
Sofitel Legend Casco Viejo, Panama City
Sheraton Grand Panama
View from property

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (880)
"Very friendly staff, cleanliness 10. Location so convenient. Breakfast buffet delicious 😋 "
Sheraton Grand Panama
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1000)
"Love it here! "
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free