Charleston Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Eagle Inn Charleston
2811 East Marshall Street Charleston MO
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
The Riverview
777 Main St Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Fairfield Inn & Suites by Marriott Cape Girardeau
433 CAPE WEST CROSSINGS Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Oct 21 - Sat, Oct 24
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$128
Roundtrip
found 22 hours ago
Thu, Oct 22 - Tue, Oct 27
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$177
Roundtrip
found 22 hours ago
Thu, Oct 22 - Tue, Oct 27
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$177
Roundtrip
found 22 hours ago
Thu, Oct 22 - Tue, Oct 27
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$183
Roundtrip
found 22 hours ago
Tue, Oct 20 - Tue, Oct 27
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$197
Roundtrip
found 22 hours ago
Best points of interest in Charleston
- Mississippi River Vacations
- Shawnee National Forest Vacations
- Ohio River Vacations
- Southeast Missouri State University Vacations
- Century Casino & Hotel Cape Girardeau Vacations
- Ohio River Valley Vacations
- Columbus-Belmont State Park Vacations
- Riverfront Bridge Park Vacations
- Riverfront Park Vacations
- Cape Splash Family Aquatic Center Vacations
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More Types of Hotels
- Hotels with WiFi in Charleston
- Hotel with wifi in Charleston
- Pet-friendly Hotels in Charleston
- Hotels with Air Conditioning in Charleston
- Hotels with a Pool in Charleston
- Hotels with Complimentary Breakfast in Charleston
- Cheap Hotels in Charleston
- Family Hotels in Charleston
- Hotels with Bars in Charleston
- Resorts & Hotels with Spas in Charleston
- Hotels with smoking rooms in Charleston