Drury Plaza Hotel Cape Girardeau Conference Center
Relax with a rejuvenating soak in the spa tub or get energized with a workout at our state-of-the-art gym.
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At Drury Plaza Hotel Cape Girardeau Conference Center, unwind in the spa tub or take a refreshing dip in the indoor pool. Savor a delicious breakfast buffet and enjoy lunch or dinner at The Southerner restaurant. With free WiFi, laundry facilities, and an on-site gym, this hotel has everything you need to stay connected and relaxed. Previous guests rave about the breakfast and helpful staff.
Reviews
9.6 out of 10
Exceptional
Popular amenities
Room options
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Showing 23 of 23 rooms
View all photos for Suite, 1 King Bed with Sofa bed (Sofa Sleeper, 2 Rooms)

Suite, 1 King Bed with Sofa bed (Sofa Sleeper, 2 Rooms)
10.0 out of 10
Exceptional
(11 reviews)
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Room, 1 King Bed
9.4 out of 10
Exceptional
(47 reviews)
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Room, 1 King Bed, Hearing Accessible (Hearing Accessible)
9.6 out of 10
Exceptional
(9 reviews)
View all photos for Suite, Multiple Beds (Sofa Sleeper, 2 Rooms)

Suite, Multiple Beds (Sofa Sleeper, 2 Rooms)
9.6 out of 10
Exceptional
(8 reviews)
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Room, 2 Queen Beds
9.8 out of 10
Exceptional
(103 reviews)
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Room, 2 Queen Beds, Hearing Accessible (Hearing Accessible)
9.2 out of 10
Wonderful
(20 reviews)
View all photos for Room, 2 Queen Beds (Upper Floor)

Room, 2 Queen Beds (Upper Floor)
9.8 out of 10
Exceptional
(6 reviews)
View all photos for Room, 1 King Bed (Upper Floor)

Room, 1 King Bed (Upper Floor)
9.6 out of 10
Exceptional
(5 reviews)
View all photos for Suite, 1 King Bed with Sofa bed (Upper Floor, Sofa Sleeper, 2 Rooms)

Suite, 1 King Bed with Sofa bed (Upper Floor, Sofa Sleeper, 2 Rooms)
9.2 out of 10
Wonderful
(7 reviews)
View all photos for Suite, Multiple Beds (Upper Floor, Sofa Sleeper, 2 Rooms)

Suite, Multiple Beds (Upper Floor, Sofa Sleeper, 2 Rooms)
8.8 out of 10
Excellent
(3 reviews)
View all photos for Room, Multiple Beds (Sofabed)

Room, Multiple Beds (Sofabed)
10.0 out of 10
Exceptional
(4 reviews)
View all photos for Room, Multiple Beds (Upper Flor, Sofa Sleeper)

Room, Multiple Beds (Upper Flor, Sofa Sleeper)
10.0 out of 10
Exceptional
(3 reviews)
View all photos for Room, 2 Queen Beds, Hearing Accessible (Sofa Sleeper)

Room, 2 Queen Beds, Hearing Accessible (Sofa Sleeper)
10.0 out of 10
Exceptional
(3 reviews)
View all photos for Suite, 1 King Bed with Sofa bed, Hearing Accessible (Sofa Sleeper, 2 Rooms)

Suite, 1 King Bed with Sofa bed, Hearing Accessible (Sofa Sleeper, 2 Rooms)
10.0 out of 10
Exceptional
(1 review)
View all photos for Suite, 2 Queen Beds, Hearing Accessible (Sofa Sleeper, 2 Rooms)

Suite, 2 Queen Beds, Hearing Accessible (Sofa Sleeper, 2 Rooms)
9.8 out of 10
Exceptional
(6 reviews)
View all photos for Room, 2 Queen Beds, Hearing Accessible (Upper Floor)

Room, 2 Queen Beds, Hearing Accessible (Upper Floor)
9.0 out of 10
Wonderful
(2 reviews)
View all photos for Suite, 1 King Bed with Sofa bed, Hearing Accessible (Upper Floor,Sofa Sleeper,Tub,2 Rooms)

Suite, 1 King Bed with Sofa bed, Hearing Accessible (Upper Floor,Sofa Sleeper,Tub,2 Rooms)
10.0 out of 10
Exceptional
(1 review)
View all photos for Room, 1 King Bed, Hearing Accessible (Roll in Shower)

Room, 1 King Bed, Hearing Accessible (Roll in Shower)
9.4 out of 10
Exceptional
(6 reviews)
View all photos for Room, 1 King Bed, Hearing Accessible (Upper Floor, Roll-in Shower)

Room, 1 King Bed, Hearing Accessible (Upper Floor, Roll-in Shower)
View all photos for Room, 1 King Bed, Hearing Accessible (Upper Floor, Tub)

Room, 1 King Bed, Hearing Accessible (Upper Floor, Tub)
8.0 out of 10
Very good
(2 reviews)
View all photos for Suite, 2 Queen Beds, Hearing Accessible (Upper Floor,Sofa Sleeper,Tub, 2 Rooms)

Suite, 2 Queen Beds, Hearing Accessible (Upper Floor,Sofa Sleeper,Tub, 2 Rooms)
9.4 out of 10
Exceptional
(3 reviews)
View all photos for Room, 2 Queen Beds, Hearing Accessible (Tub)

Room, 2 Queen Beds, Hearing Accessible (Tub)
9.4 out of 10
Exceptional
(14 reviews)
View all photos for Room, 2 Queen Beds, Hearing Accessible (Upper Floor, Tub)

Room, 2 Queen Beds, Hearing Accessible (Upper Floor, Tub)
About the neighborhood

3351 Percy Drive, Cape Girardeau, MO, 63701
What's nearby
Riverfront Bridge Park6 min drive - 5.5 miles
Southeast Missouri State University7 min drive - 5.5 miles- Cape Splash Family Aquatic Center5 min drive - 4.4 miles
- Century Casino & Hotel Cape Girardeau9 min drive - 7.0 miles
- Hunter Valley Winery21 min drive - 19.8 miles
Getting around
- Cape Girardeau, MO (CGI-Cape Girardeau Municipal)10 min drive
Restaurants
- Chick-fil-A13 min walk
- Rhodes3 min drive
- McDonald's14 min walk
- Panera Bread10 min walk
- Taco Bell19 min walk
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- Pool
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Property amenities
Room amenities
Policies
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
- Deposit: USD 50 per accommodation, per stay
We have included all charges provided to us by the property.
Optional extras
- Pet fee: USD 50 per accommodation, per night
- Service animals are exempt from fees
- Rollaway bed fee: USD 15.0 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
We should mention
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Frequently asked questions
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Reviews
Drury Plaza Hotel Cape Girardeau Conference Center Reviews
9.6
Exceptional
9.8
Cleanliness
9.8
Amenities
9.8
Staff & service
9.6
Property conditions & facilities
Reviews
Verified
Jun 2, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stayed 1 night in May 2026
Verified
10/10 Excellent
Darlene F.
Jun 1, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Darlene F.
Stayed 1 night in May 2026
Verified
10/10 Excellent
Linda
Apr 16, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Linda
Stayed 5 nights in Apr 2026
Verified
10/10 Excellent
Troy
May 28, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Troy
Stayed 1 night in May 2026
Verified
8/10 Good
Jasper
May 22, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jasper
Stayed 3 nights in May 2026
Verified
10/10 Excellent
Caroline
Apr 13, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Caroline
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
Cynthia
Mar 20, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Cynthia
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
SUSAN
Apr 16, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
SUSAN
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
Shirley
Mar 17, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Shirley
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Laura
Mar 16, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Laura
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Brenda
Apr 17, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brenda
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
Mark
Apr 5, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Mark
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
David
Mar 3, 2026
David
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Brian
Mar 30, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brian
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Kay
Feb 1, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Kay
Stayed 1 night in Jan 2026
Verified
10/10 Excellent
Troy
Apr 6, 2026
Troy
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
Stephen
Mar 20, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stephen
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Shellie
Feb 11, 2026
Liked: Cleanliness, staff & service, amenities
Shellie
Stayed 1 night in Feb 2026
Verified
10/10 Excellent
Mario
Feb 15, 2026
Mario
Stayed 1 night in Oct 2025
Verified
8/10 Good
ANDREA
Dec 31, 2025
Liked: Cleanliness, staff & service, amenities
ANDREA
Stayed 2 nights in Dec 2025
Verified
10/10 Excellent
Ronald
Feb 25, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Ronald
Stayed 1 night in Feb 2026
Verified
10/10 Excellent
Adrienne
Mar 2, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Adrienne
Stayed 2 nights in Feb 2026
Verified
10/10 Excellent
Chad
Dec 27, 2025
Liked: Cleanliness, staff & service, amenities
Chad
Stayed 1 night in Dec 2025
Verified
10/10 Excellent
Carter
Jan 16, 2026
Liked: Cleanliness, property conditions & facilities
Carter
Stayed 1 night in Jan 2026
Verified
10/10 Excellent
Terrill
Jan 17, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Terrill
Stayed 1 night in Jan 2026








