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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Travelers can enjoy the indoor pool and spa treatments after exploring the area, then wake up to a delicious breakfast that makes mornings easy

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
Free breakfast - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
Indoor pool, open 8 AM to 11 PM, sun loungers - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
Exterior - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers comfort in a rural setting with free breakfast and an indoor pool. Relax at the onsite spa and sun loungers by the pool. Dry cleaning, laundry services, and luggage storage are available, with highly praised staff.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Parking included
  • Free WiFi
  • Air conditioning

Room options

Available filters for rooms
Showing 9 of 9 rooms

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.4 out of 10
Exceptional
(6 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(55 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillowtop bed
Down duvet
  • 37 sq m
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • 37 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillowtop bed
Down duvet
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Down duvet
Premium bedding
  • Sleeps 2
  • 1 King Bed

About the neighborhood

Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Visit our Cape Girardeau travel guide
Map
3253 William Street, Cape Girardeau, MO, 63701

What's nearby

  • View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park
    Riverfront Bridge Park
    6 min drive - 4.4 miles
  • Panorama of Academic Hall, Southeast Missouri State University
    Southeast Missouri State University
    6 min drive - 3.9 miles
  • Saint Francis Medical Center
    6 min walk - 0.4 miles
  • Isle Casino Cape Girardeau
    8 min drive - 5.7 miles
  • Show Me Center
    9 min drive - 5.7 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    10 min drive

Restaurants

  • Chick-fil-A
    7 min walk
  • Rhodes
    20 min walk
  • McDonald's
    10 min walk
  • White Castle
    10 min walk
  • Wings Etc.
    9 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel near Shawnee National Forest
You can look forward to free breakfast, dry cleaning/laundry services, and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the onsite spa. In addition to a business center, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
  • Swimming pool along with sun loungers
  • Free self parking
  • An indoor pool, a banquet hall, and luggage storage
  • 1 meeting room, free newspapers, and a front-desk safe
  • Guest reviews speak highly of the breakfast and helpful staff
Room features
All 102 rooms feature comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property.
More amenities include:
  • Pillowtop mattresses and down comforters
  • Bathrooms with free toiletries and hair dryers
  • 52-inch flat-screen TVs with premium channels
  • Separate sitting areas, mini fridges, and microwaves

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  • Breakfast included
  • Parking included
  • Free WiFi
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–11 PM.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?

No, pets are not allowed at this property.

How much is parking?

Self parking is free at this property.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?

Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 mi (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away.

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Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

9.6

Cleanliness

9.2

Location

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 780 out of 1004 reviews
Rating 8 - Good. 152 out of 1004 reviews
Rating 6 - Okay. 39 out of 1004 reviews
Rating 4 - Poor. 16 out of 1004 reviews
Rating 2 - Terrible. 17 out of 1004 reviews

Reviews

10/10 Excellent

Rex

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026

10/10 Excellent

Dawn

Liked: Cleanliness, amenities, property conditions & facilities
Everyone kind & place very clean.
Stayed 1 night in Jan 2026

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice room. There was a little noise from other rooms or perhaps from the hallways. The breakfast was very good.
Stayed 1 night in Jan 2026

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly.
Stayed 1 night in Dec 2025

10/10 Excellent

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great staff and clean rooms.
Stayed 1 night in Sep 2025

10/10 Excellent

Kelly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was right off the interstate with lots of restaurant options
Stayed 1 night in Sep 2025

10/10 Excellent

Carey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very Friendly check in Parking lot was very Safe A lot of know restaurants within walking distance from Hotel,Very Clean.
Stayed 2 nights in Aug 2025

10/10 Excellent

Gretchen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe
Stayed 1 night in Oct 2025

10/10 Excellent

Christine

We had an excellent comfortable stay here! Loved our room and full breakfast.
Stayed 2 nights in Jun 2025

10/10 Excellent

Christina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fast, very friendly desk service. We were allowed to check in a little early, a big plus since we arrived at 2 for a wedding at 3!! We got down for breakfast 30 minutes before the end of closing and it was evident. But the pancakes were great! Thanks for everyone's service!
Stayed 1 night in Nov 2025

8/10 Good

Carrie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great room and good breakfast. Great place to stay with central location.
Stayed 1 night in May 2025

10/10 Excellent

Cherish

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We got greeted with such a friendly smile and attitude as soon as we got in. The room was clean and roomy. Would highly recommend and come back.
Stayed 1 night in Sep 2025

10/10 Excellent

Laura

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Lovely stay

Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious.
Stayed 1 night in Aug 2025

10/10 Excellent

Crystal

Liked: Cleanliness, staff & service, property conditions & facilities
Pool is nice! Place is perfect
Stayed 1 night in Jul 2025

10/10 Excellent

Pam

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great room with everything i needed!!!
Stayed 1 night in Jul 2025

10/10 Excellent

Josephine

Liked: Cleanliness, property conditions & facilities
This was our 2nd time staying at this hotel while traveling. Hotel is very well maintained, easy access off interstate and has a number of restaurants and gas stations for your convenience.
Stayed 1 night in Jun 2025

10/10 Excellent

Nick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was super helpful at check in and very courteous throughout the whole stay
Stayed 2 nights in Apr 2025

10/10 Excellent

Frank

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff is phenomenal, and the room was very clean, accommodating all my needs.
Stayed 1 night in May 2025

8/10 Good

Shivani

Liked: Cleanliness, staff & service, property conditions & facilities
Awesome. Comfortable and clean rooms. Very convenient location.
Stayed 1 night in Jul 2025

8/10 Good

Bernadette

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
staff was very friendly. room clean
Stayed 2 nights in Jul 2025

10/10 Excellent

sylvian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property is situated in a great spot! Lots to choose from for dining.
Stayed 2 nights in May 2025

10/10 Excellent

JUAN

Liked: Amenities
Cleanliness and staff really helpful
Stayed 1 night in May 2025

10/10 Excellent

Penny

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay

Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!
Stayed 1 night in Jul 2025

10/10 Excellent

Lucas

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent experience for our family. Every member of the staff we encountered were great. Breakfast was good, room was clean and spacious. Above and beyond expectations, would absolutely stay here again!
Stayed 2 nights in Jun 2025

10/10 Excellent

Taylor

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean hotel. The beds were not hard as brick very comfortable.
Stayed 1 night in May 2025