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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Property class: 2.5

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Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier. - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
A hotel room with a bed, desk, chair, TV, and a small kitchenette area. - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool. - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall. - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions. - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, you can look forward to free breakfast, dry cleaning/laundry services, and a gym. Take some time to relax at the onsite spa. In addition to a business center, guests can connect to free in-room WiFi.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning

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Room options

Available filters for rooms
Showing 9 of 9 rooms

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

A hotel room with two beds, a desk, a chair, a sofa, and a framed picture on the wall.

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free wired internet

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

A hotel room with a bed, a desk, a chair, a sofa, and a mirror.

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Suite, 1 King Bed

A hotel room with a bed, a desk, a chair, and a couch.

Suite, 1 King Bed

9.8 out of 10
Exceptional
(40 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Suite, 2 Queen Beds

A hotel room with two beds, a desk, a chair, a sofa, and a framed picture on the wall.

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(70 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free wired internet

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

A hotel room with two beds, a desk, a chair, and a sofa.

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(17 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free wired internet

View all photos for Standard Room, 1 Queen Bed

A hotel room with a bed, a desk, a chair, a sofa, and a mirror.

Standard Room, 1 Queen Bed

9.4 out of 10
Exceptional
(6 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free wired internet

View all photos for Standard Room

A bed with white bedding and two pillows against a wooden headboard.

Standard Room

8.8 out of 10
Excellent
(6 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Suite, 1 Bedroom (Feature)

A hotel room with a bed, a desk, a chair, a sofa, and a mirror.

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free wired internet

View all photos for Suite, 1 King Bed, Accessible (Mobility)

A hotel room with a bed, a desk, a chair, a sofa, and a mirror.

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

About the neighborhood

Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Visit our Cape Girardeau travel guide
Map
3253 William Street, Cape Girardeau, MO, 63701

What's nearby

  • A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.
    Southeast Missouri State University
    7 min drive - 3.7 miles
  • A rock formation with a tree growing in the center.
    Giant City State Park
    54 min drive - 49.1 miles
  • Riverfront Park
    7 min drive - 5.5 miles
  • Century Casino & Hotel Cape Girardeau
    9 min drive - 6.5 miles
  • Hunter Valley Winery
    22 min drive - 20.2 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    10 min drive

Restaurants

  • Chick-fil-A
    7 min walk
  • McDonald's
    10 min walk
  • Taco Bell
    12 min walk
  • Qdoba Mexican Eats
    13 min walk
  • Panera Bread
    2 min walk

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

  • American Express
  • Diners Club
  • Discover
  • JCB International
  • Mastercard
  • Visa

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–11 PM.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?

No, pets are not allowed at this property.

How much is parking?

Self parking is free at this property.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?

Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 mi (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Southeast Missouri State University and Cape Splash Family Aquatic Center are also within 3 mi (5 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

9.6

Cleanliness

9.4

Location

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 772 out of 1000 reviews
Rating 8 - Good. 148 out of 1000 reviews
Rating 6 - Okay. 39 out of 1000 reviews
Rating 4 - Poor. 20 out of 1000 reviews
Rating 2 - Terrible. 21 out of 1000 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location, beds were awesome & staff were friendly & accommodating!
Stayed 3 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful.
Stayed 3 nights in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good breakfast ( a bit crowded), roomy suite, good location, good value for a weekend stay
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everyone was great and rooms were nice and breakfast was great.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff with tips on what to do in town.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place was awesome and clean and convenient to everything and the suites are awesome
Stayed 3 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This place was awesome hands down! The staff was extremely accommodating and friendly. Thank you Madison for a great check in experience. Of all the hotels we stayed at over our road trip this weekend this was the best deal and the nicest establishment by far. The receptionist even gave my children little toys out the treasure chest as we were checking out. Thank y'all again! Will def be back if I am ever in the area.
Stayed 1 night in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was nothing to dislike. Was nice to have many eating options within a safe walking distance.
Stayed 3 nights in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This establishment was very clean, amazingly maintained, and it is in the just the right location of restaurants, the staff was very friendly and helpful. I most definitely will be making every stop a holiday express experience.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice customer service. I liked the access to washer and dryer, as well as cookies being served in the evening. I like the indoor pool and the gym. Is closed to many restaurants and showing mall.
Stayed 3 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was very spacious and great water pressure. Staff very kind to us, the breakfast was great as well
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Employees were very polite and accommodating. Complimentary breakfast was a good variety and plenty of it!! Room was very clean and organized. Parking was plentiful and convieient. Overall, very satisfied!! Will choose to stay jrrr again!!
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities
Beds and pillows were very comfortable. Shower had excellent water pressure and consistent temperature. Breakfast was good and had many options.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel is in a convenient central area. Was clean and staff was friendly.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was clean and the room are comfortable. It is located right off the interstate near a lot of restaurants, shopping and large medical facility.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room staff is very nice parking it great
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was recommended by a friend of ours. The hotel staff were great. It was clean and quiet. Me and my husband enjoyed our stay.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was excellent. Staff was very friendly and helpful.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
For the price, this stay exceeded my expectations. Everything was clean and the staff were very helpful. The suite we stayed in had many helpful features. Breakfast also was delicious and there were many options.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff was very friendly.
Stayed 2 nights in Nov 2025