Charleston Vacations

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Top Hotel Deals

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
1.66 km from city center
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
2.35 km from city center
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
Eagle Inn Charleston

Eagle Inn Charleston

2 out of 5
2811 East Marshall Street, Charleston, MO
3.73 km from city center
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
45.83 km from city center
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
47.19 km from city center
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
46.69 km from city center
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
16.5 km from city center
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
46.57 km from city center
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
46.85 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
45.21 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
16.89 km from city center
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
16.51 km from city center
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
16.98 km from city center
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
45.29 km from city center
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
46.86 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Oct 16 - Sun, Oct 19
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$122 Roundtrip, found 2 days ago
$122
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Oct 16 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Oct 19, priced at $122 found 2 days ago
Delta
Thu, Oct 16 - Mon, Oct 20
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$147 Roundtrip, found 2 days ago
$147
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 16 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Oct 20, priced at $147 found 2 days ago
Spirit Airlines
Mon, Aug 25 - Sun, Aug 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$172 Roundtrip, found 1 day ago
$172
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Aug 25 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Aug 31, priced at $172 found 1 day ago
United
Thu, Aug 28 - Sun, Aug 31
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$173 Roundtrip, found 5 days ago
$173
Roundtrip
found 5 days ago
Select United flight, departing Thu, Aug 28 from Denver Intl. to Lambert-St. Louis Intl., returning Sun, Aug 31, priced at $173 found 5 days ago
American Airlines
Wed, Sep 24 - Mon, Sep 29
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$203 Roundtrip, found 22 hours ago
$203
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Sep 24 from Philadelphia Intl. to Lambert-St. Louis Intl., returning Mon, Sep 29, priced at $203 found 22 hours ago