Charleston Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St, Charleston, MO
2.35 km from city center
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
Quality Inn Charleston - Sikeston
102 Drake St, I-57 Exit 10, Charleston, MO
1.66 km from city center
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Eagle Inn Charleston
2811 East Marshall Street, Charleston, MO
3.73 km from city center
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
The Riverview
777 Main St, Cape Girardeau, MO
45.83 km from city center
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
47.19 km from city center
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
16.98 km from city center
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
46.57 km from city center
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
45.21 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
16.5 km from city center
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
46.69 km from city center
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
46.86 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
16.51 km from city center
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
46.85 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Thu, Jun 12 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$120 Roundtrip, found 1 day ago
$120
Roundtrip
found 1 day ago
Sat, Oct 11 - Sat, Oct 18
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$126 Roundtrip, found 2 days ago
$126
Roundtrip
found 2 days ago
Sat, May 24 - Wed, May 28
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$162 Roundtrip, found 2 days ago
$162
Roundtrip
found 2 days ago
Tue, May 20 - Wed, May 21
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$162 Roundtrip, found 2 days ago
$162
Roundtrip
found 2 days ago
Best points of interest in Charleston
- Shawnee National Forest Vacations
- Mississippi River Vacations
- Ohio River Vacations
- Southeast Missouri State University Vacations
- Isle Casino Cape Girardeau Vacations
- Riverfront Bridge Park Vacations
- Cape Splash Family Aquatic Center Vacations
- Columbus-Belmont State Park Vacations
- Riverfront Park Vacations
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More Types of Hotels
- Hotels with WiFi in Charleston
- Hotel with wifi in Charleston
- Pet-friendly Hotels in Charleston
- Hotels with Air Conditioning in Charleston
- Hotels with a Pool in Charleston
- Hotels with Complimentary Breakfast in Charleston
- Cheap Hotels in Charleston
- Family Hotels in Charleston
- Hotels with Bars in Charleston
- Resorts & Hotels with Spas in Charleston
- Hotels with smoking rooms in Charleston