Charleston Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Quality Inn Charleston - Sikeston
102 Drake St, I-57 Exit 10, Charleston, MO
1.66 km from city center
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St, Charleston, MO
2.35 km from city center
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
Eagle Inn Charleston
2811 East Marshall Street, Charleston, MO
3.73 km from city center
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
47.19 km from city center
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
The Riverview
777 Main St, Cape Girardeau, MO
45.83 km from city center
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
16.5 km from city center
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
46.57 km from city center
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
45.21 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
46.85 km from city center
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
16.89 km from city center
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
46.69 km from city center
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
16.51 km from city center
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St., Cape Girardeau, MO
45.29 km from city center
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sat, Aug 16 - Sat, Aug 23
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$134 Roundtrip, found 6 days ago
$134
Roundtrip
found 6 days ago
Tue, Oct 7 - Tue, Oct 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$137 Roundtrip, found 11 hours ago
$137
Roundtrip
found 11 hours ago
Fri, Jul 18 - Mon, Jul 21
LGA
LaGuardia
STL
Lambert-St. Louis Intl.
$151 Roundtrip, found 1 day ago
$151
Roundtrip
found 1 day ago
Wed, Sep 24 - Mon, Sep 29
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 3 days ago
$197
Roundtrip
found 3 days ago
Wed, Sep 24 - Mon, Sep 29
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago
Best points of interest in Charleston
- Shawnee National Forest Vacations
- Mississippi River Vacations
- Ohio River Vacations
- Southeast Missouri State University Vacations
- Isle Casino Cape Girardeau Vacations
- Riverfront Bridge Park Vacations
- Cape Splash Family Aquatic Center Vacations
- Columbus-Belmont State Park Vacations
- Riverfront Park Vacations
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More Types of Hotels
- Hotels with WiFi in Charleston
- Hotel with wifi in Charleston
- Pet-friendly Hotels in Charleston
- Hotels with Air Conditioning in Charleston
- Hotels with a Pool in Charleston
- Hotels with Complimentary Breakfast in Charleston
- Cheap Hotels in Charleston
- Family Hotels in Charleston
- Hotels with Bars in Charleston
- Resorts & Hotels with Spas in Charleston
- Hotels with smoking rooms in Charleston