2025 4 Star Hotels in Mission District

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Featured Mission District 4 Star Hotels

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Hotel Riu Plaza Fisherman's Wharf
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St, San Francisco, CA
Hyatt Centric Fisherman's Wharf San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Hyatt Regency San Francisco
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
200 Marina Blvd, Berkeley, CA
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel Berkeley Marina
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Club Quarters Hotel in San Francisco
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St, San Francisco, CA
Parc 55 San Francisco - A Hilton Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Hilton San Francisco Financial District
The Westin San Francisco Airport

The Westin San Francisco Airport

4 out of 5
1 Old Bayshore Hwy, Millbrae, CA
The Westin San Francisco Airport
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd, San Francisco, CA
Grand Hyatt at SFO
See all 4,747 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.