
Southern Minnesota Vacation Packages for 2025
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Top Hotel Deals

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
124.02 km from city center
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
123.79 km from city center
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
122.24 km from city center
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
125.08 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
123.82 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
123.62 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...

Aspen Select
1215 2nd St SW, Rochester, MN
122.48 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
124.55 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
124.04 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW, Suite A, Rochester, MN
122.72 km from city center
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...

St James Hotel, a Historic Hotel of America
406 Main St., Red Wing, MN
130.46 km from city center
Stay at this 3.5-star spa hotel in Red Wing. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw, Rochester, MN
122.19 km from city center
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...

Express Suites Riverport Inn & Suites
900 Bruski Dr, Winona, MN
191.27 km from city center
Stay at this 3-star business-friendly hotel in Winona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Aug 26 - Sun, Aug 31
PHX
Sky Harbor Intl.
MSP
Minneapolis - St. Paul Intl.
$106 Roundtrip, found 12 hours ago
$106
Roundtrip
found 12 hours ago

Wed, Aug 6 - Wed, Aug 13
DEN
Denver Intl.
FSD
Sioux Falls Regional
$114 Roundtrip, found 3 days ago
$114
Roundtrip
found 3 days ago
Mon, Sep 8 - Sat, Sep 13
PHX
Sky Harbor Intl.
MSP
Minneapolis - St. Paul Intl.
$147 Roundtrip, found 6 days ago
$147
Roundtrip
found 6 days ago

Tue, Jul 15 - Wed, Jul 23
ATL
Hartsfield-Jackson Atlanta Intl.
MSP
Minneapolis - St. Paul Intl.
$152 Roundtrip, found 3 days ago
$152
Roundtrip
found 3 days ago

Mon, Sep 8 - Sat, Sep 13
PHX
Sky Harbor Intl.
MSP
Minneapolis - St. Paul Intl.
$157 Roundtrip, found 6 days ago
$157
Roundtrip
found 6 days ago
Best neighborhoods in Southern Minnesota
Best points of interest in Southern Minnesota
- Mayo Clinic Vacations
- Mayo Clinic Hospital - Saint Marys Campus Vacations
- Treasure Island Casino Vacations
- Minnesota State University Vacations
- Mayo Civic Center Vacations
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- Lake Pepin Vacations
- Apache Mall Vacations
- Rochester Recreation Center Vacations
- Winona State University Vacations
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