South San Diego Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
South San Diego Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
La Jolla Cove Suites
Village of La Jolla
Save 100% on your flight
Price was $1,023, price is now $629 per person
$629
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Book a stay at this beach hotel in La Jolla. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and La Jolla Cove are located nearby.
San Diego Marriott La Jolla
University City
Save 100% on your flight
Price was $1,086, price is now $744 per person
$744
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Book a stay at this business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions La Jolla Beach and Torrey Pines Golf Course are located nearby.
San Diego Mission Bay Resort
Mission Bay
Save 100% on your flight
Price was $959, price is now $692 per person
$692
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and San Diego Zoo are located nearby.
Hotel del Coronado, Curio Collection by Hilton
Historic Downtown Coronado
Save 100% on your flight
Price was $2,007, price is now $1,449 per person
$1,449
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Inn At The Park
Bankers Hill
Save 100% on your flight
Price was $1,021, price is now $741 per person
$741
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Stay at this 3-star hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Club Wyndham Harbour Lights
Downtown San Diego
Save 100% on your flight
Price was $871, price is now $641 per person
$641
per person
Feb 9 - Feb 14
found 1 day ago
Roundtrip non-stop flight included
Portland (PDX) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
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See all available trips from Columbus to South San Diego
View all tripsTop Hotel Deals
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
22.34 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
19.02 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
23.17 km from city center
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
19.63 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
21.16 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr National City CA
11.2 km from city center
Book a stay at this golf hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in our reviews. ...
Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
22.79 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
18.25 km from city center
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
19.76 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
23.52 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
27.99 km from city center
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
Hampton Inn & Suites by Hilton San Diego SeaWorld
3888 Greenwood St San Diego CA
25.03 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
The Sofia Hotel
150 W Broadway San Diego CA
19.18 km from city center
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
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See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mon, Jan 12 - Fri, Jan 16
SFO
San Francisco Intl.
SAN
San Diego Intl.
$68 Roundtrip, found 14 hours ago
$68
Roundtrip
found 14 hours ago
Tue, Mar 3 - Wed, Mar 11
SFO
San Francisco Intl.
SAN
San Diego Intl.
$97 Roundtrip, found 23 hours ago
$97
Roundtrip
found 23 hours ago
Thu, Mar 5 - Wed, Mar 11
SFO
San Francisco Intl.
SAN
San Diego Intl.
$107 Roundtrip, found 23 hours ago
$107
Roundtrip
found 23 hours ago
Sat, Jan 10 - Mon, Jan 12
SFO
San Francisco Intl.
SAN
San Diego Intl.
$132 Roundtrip, found 14 hours ago
$132
Roundtrip
found 14 hours ago
Thu, Dec 25 - Sat, Jan 10
DAL
Love Field
SAN
San Diego Intl.
$218 Roundtrip, found 2 days ago
$218
Roundtrip
found 2 days ago