Otay Mesa West Vacation Packages for 2026

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Otay Mesa West Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Los Bungalows

Los Bungalows

2.5 out of 5
Save 100% on your flight
Price was $1,384, price is now $949 per person
$949
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions Las Americas Premium Outlets and Imperial Beach are located nearby.

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was $1,997, price is now $956 per person
$956
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,958, price is now $1,224 per person
$1,224
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar

3 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,708, price is now $1,116 per person
$1,116
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
Historic Downtown Coronado
Save 100% on your flight
Price was $2,665, price is now $1,855 per person
$1,855
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
Mission Bay
Save 100% on your flight
Price was $2,524, price is now $1,773 per person
$1,773
per person
Mar 13 - Mar 20
found 21 hours ago
Roundtrip non-stop flight included
Flint (FNT) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Port of San Diego are located nearby.

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Top Hotel Deals

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
17.51 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
19.06 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
21.38 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
19.15 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
27.13 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

5 out of 5
326 Broadway San Diego CA
18.38 km from Otay Mesa West
Book a stay at this luxury hotel in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful ...
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
17.66 km from Otay Mesa West
Book a stay at this luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
26.81 km from Otay Mesa West
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
22.12 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
22.79 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
27.94 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
19.21 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
18.5 km from Otay Mesa West
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
18.19 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
22.93 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, Feb 28 - Sat, Mar 14
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$66 Roundtrip, found 6 days ago
$66
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Feb 28 from Dallas-Fort Worth Intl. to San Diego Intl., returning Sat, Mar 14, priced at $66 found 6 days ago
Southwest Airlines
Wed, Apr 15 - Sat, Apr 18
SFO
San Francisco Intl.
SAN
San Diego Intl.
$97 Roundtrip, found 5 days ago
$97
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Apr 15 from San Francisco Intl. to San Diego Intl., returning Sat, Apr 18, priced at $97 found 5 days ago
Hawaiian Airlines
Wed, Feb 25 - Wed, Mar 4
ORD
O'Hare Intl.
SAN
San Diego Intl.
$157 Roundtrip, found 20 hours ago
$157
Roundtrip
found 20 hours ago
Select Hawaiian Airlines flight, departing Wed, Feb 25 from O'Hare Intl. to San Diego Intl., returning Wed, Mar 4, priced at $157 found 20 hours ago
Alaska Airlines
Wed, Feb 18 - Wed, Feb 25
BOS
Logan Intl.
SAN
San Diego Intl.
$207 Roundtrip, found 2 days ago
$207
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Wed, Feb 18 from Logan Intl. to San Diego Intl., returning Wed, Feb 25, priced at $207 found 2 days ago
United
Sun, Sep 6 - Mon, Sep 14
EWR
Newark Liberty Intl. Airport
SAN
San Diego Intl.
$217 Roundtrip, found 2 days ago
$217
Roundtrip
found 2 days ago
Select United flight, departing Sun, Sep 6 from Newark Liberty Intl. Airport to San Diego Intl., returning Mon, Sep 14, priced at $217 found 2 days ago