Otay Mesa West Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Otay Mesa West Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
The Beau Hotel Gaslamp Quarter San Diego
Downtown San Diego
Price was $980, price is now $705 per person
$705
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.
Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $1,075, price is now $741 per person
$741
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
The Lodge at Torrey Pines
Torrey Pines
Save 100% on your flight
Price was $2,918, price is now $2,063 per person
$2,063
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Book a stay at this luxury hotel in La Jolla. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions La Jolla Cove and Torrey Pines Golf Course are located nearby.
Kona Kai San Diego
Point Loma
Save 100% on your flight
Price was $1,159, price is now $832 per person
$832
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
Alma San Diego Downtown, a Tribute Portfolio Hotel
Downtown San Diego
Price was $1,039, price is now $806 per person
$806
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Book a stay at this boutique hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Paradise Point Resort & Spa
Mission Bay
Save 100% on your flight
Price was $1,435, price is now $1,115 per person
$1,115
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
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Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
18.19 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
The Sofia Hotel
150 W Broadway San Diego CA
18.5 km from Otay Mesa West
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
Best Western Seven Seas
411 Hotel Circle South San Diego CA
22.89 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
19.21 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
17.51 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
30.62 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
26.81 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Bahia Resort Hotel
998 W Mission Bay Dr San Diego CA
28.17 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
22.93 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
16.29 km from Otay Mesa West
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
The Alcala Hotel Mission Valley/Seaworld
San Diego CA
23.99 km from Otay Mesa West
Book a stay at this golf hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
27.94 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
22.12 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Tue, Jul 21 - Tue, Jul 28
SFO
San Francisco Intl.
SAN
San Diego Intl.
$66 Roundtrip, found 1 day ago
$66
Roundtrip
found 1 day ago
Wed, Aug 19 - Tue, Aug 25
PDX
Portland Intl.
SAN
San Diego Intl.
$145 Roundtrip, found 1 hour ago
$145
Roundtrip
found 1 hour ago
Tue, Sep 29 - Tue, Oct 6
PAE
Seattle Paine Field Intl. Airport
SAN
San Diego Intl.
$187 Roundtrip, found 6 days ago
$187
Roundtrip
found 6 days ago
Sat, Sep 12 - Tue, Sep 15
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$189 Roundtrip, found 4 hours ago
$189
Roundtrip
found 4 hours ago
Tue, Jun 30 - Tue, Jul 7
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$257 Roundtrip, found 3 days ago
$257
Roundtrip
found 3 days ago