South Jefferson Vacation Packages for 2025
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South Jefferson Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Days Inn by Wyndham Roanoke/Hollins Near I-81
Alpine Hills
Price was $482, price is now $401 per person
$401
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Eleanor D. Wilson Museum and Carvins Cove are located nearby.
The Liberty Trust
Downtown Roanoke
Price was $772, price is now $569 per person
$569
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Stay at this 4-star luxury hotel in Roanoke. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Roanoke Pinball Museum and History Museum & Historical Society of Western Virginia are located nearby.
The West End Flats
West End
Price was $635, price is now $483 per person
$483
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Stay at this 4.5-star luxury aparthotel in Roanoke. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Shaftman Performance Hall and Jefferson Center are located nearby.
Fire Station One Boutique Hotel
Downtown Roanoke
Price was $1,027, price is now $791 per person
$791
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Stay at this hotel in Roanoke. Enjoy free WiFi, daily housekeeping, and a snack bar/deli. Popular attractions Arts Council of the Blue Ridge and Roanoke Pinball Museum are located nearby.
Natural Bridge Hotel, Trademark Collection by Wyndham
Price was $784, price is now $652 per person
$652
per person
Nov 23 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Stay at this 3-star business-friendly hotel in Natural Bridge. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Virginia Safari Park and The Toy Museum at Natural Bridge of Virginia are located nearby.
Affordable Corporate Suites of Overland Drive
Price was $600, price is now $511 per person
$511
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Roanoke (ROA)
Stay at this motel in Roanoke. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions Sun Tennis Center and Tanglewood Mall are located nearby.
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SpringHill Suites by Marriott Roanoke
301 Reserve Ave SW, Roanoke, VA
0.4 km from South Jefferson
Stay at this 3-star business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in ...
The Liberty Trust
101 S Jefferson St, Roanoke VA 24011, Roanoke, VA
1.54 km from South Jefferson
Stay at this 4-star luxury hotel in Roanoke. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
Baymont by Wyndham Salem Roanoke Area
179 Sheraton Drive, I-81 Exit 141, Salem, VA
10.59 km from South Jefferson
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Country Inn & Suites by Radisson, Roanoke, VA
7860 Plantation Rd, Roanoke, VA
10.86 km from South Jefferson
Stay at this 3-star business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Roanoke Salem
140 Sheraton Dr, Salem, VA
10.51 km from South Jefferson
Stay at this 3-star business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Spark by Hilton Roanoke Civic Center
815 Gainsboro Rd Nw, Roanoke, VA
2.58 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Spark by Hilton Roanoke Airport
3695 Thirlane Rd Nw, Roanoke, VA
6.62 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Valley View Mall and Regal Valley ...
Days Inn by Wyndham Roanoke/Hollins Near I-81
8118 Plantation Road, Roanoke, VA
11.33 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Motel 6 Salem, VA
301 Wildwood Road, Salem, VA
14.09 km from South Jefferson
Book a stay at this golf motel in Salem. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
Tru By Hilton Roanoke Hollins
8161 Gander Way, Roanoke, VA
11.16 km from South Jefferson
Stay at this hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton
110 Shenandoah Ave Ne, Roanoke, VA
1.81 km from South Jefferson
Stay at this 4-star luxury hotel in Roanoke. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition ...
Comfort Suites Inn at Ridgewood Farm
2898 Keagy Rd, Salem, VA
8.2 km from South Jefferson
Book a stay at this golf hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Holiday Inn Roanoke-Tanglewood-Rt 419&i581 by IHG
4468 Starkey Road, Roanoke, VA
5.21 km from South Jefferson
Stay at this 3-star business-friendly hotel in Roanoke. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
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See all available properties in South Jefferson
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sat, Oct 11 - Tue, Oct 14
ORD
O'Hare Intl.
ROA
Roanoke Regional
$309 Roundtrip, found 5 days ago
$309
Roundtrip
found 5 days ago
Sat, Oct 11 - Thu, Oct 16
ORD
O'Hare Intl.
ROA
Roanoke Regional
$359 Roundtrip, found 5 days ago
$359
Roundtrip
found 5 days ago
Mon, Oct 13 - Fri, Oct 17
PHL
Philadelphia Intl.
ROA
Roanoke Regional
$508 Roundtrip, found 6 days ago
$508
Roundtrip
found 6 days ago
Sun, Oct 12 - Fri, Oct 17
PHL
Philadelphia Intl.
ROA
Roanoke Regional
$517 Roundtrip, found 6 days ago
$517
Roundtrip
found 6 days ago