Vacation Packages to Santa Cruz for 2025

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Top Hotel Deals

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
3.03 km from city center
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ventura Mall and Patio Design LifeStyle ...
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
2.67 km from city center
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
1.52 km from city center
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
3.3 km from city center
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
3.49 km from city center
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

3.5 out of 5
Calle Pablo Sanz 29 Equipetrol, Santa Cruz
2.82 km from city center
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, room service, and daily housekeeping. Popular attractions Ventura Mall and Santa Cruz Zoo are located ...
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
2.47 km from city center
Stay at this 4-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
14.36 km from city center
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

5 out of 5
AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz
3.3 km from city center
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle ...
Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
1.42 km from city center
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
Lido Hotel

Lido Hotel

3 out of 5
Calle 21 de Mayo 527, Santa Cruz
0.59 km from city center
Stay at this 3-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Arenal Park and Ethno-folkloric Museum are located ...
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
2.75 km from city center
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
Hotel Maywa

Hotel Maywa

4 out of 5
2do anillo av.santacruz #1007, Santa Cruz, Santa Cruz Department
1.95 km from city center
Stay at this 4-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Blacutt Square and Santa ...
Senses Boutique Hotel

Senses Boutique Hotel

3.5 out of 5
Calle 24 de Septiembre, Esq. Sucre No 5, Plaza Principal, Santa Cruz
0.05 km from city center
Stay at this 3.5-star family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Franco Aleman Cultural ...
Hotel Cortez

Hotel Cortez

3.5 out of 5
Av. Cristobal de Mendoza 280, Santa Cruz
1.4 km from city center
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Municipal Library and Arenal Park are located ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Mon, Aug 25 - Sun, Aug 31
JFK
New York
VVI
Santa Cruz
$768 Roundtrip, found 8 hours ago
$768
Roundtrip
found 8 hours ago
Select avianca flight, departing Mon, Aug 25 from New York to Santa Cruz, returning Sun, Aug 31, priced at $768 found 8 hours ago
Copa
Mon, Aug 25 - Sun, Aug 31
JFK
New York
VVI
Santa Cruz
$852 Roundtrip, found 8 hours ago
$852
Roundtrip
found 8 hours ago
Select Copa flight, departing Mon, Aug 25 from New York to Santa Cruz, returning Sun, Aug 31, priced at $852 found 8 hours ago
JetBlue Airways
Mon, Aug 25 - Sun, Aug 31
JFK
New York
VVI
Santa Cruz
$1,030 Roundtrip, found 8 hours ago
$1,030
Roundtrip
found 8 hours ago
Select JetBlue Airways flight, departing Mon, Aug 25 from New York to Santa Cruz, returning Sun, Aug 31, priced at $1,030 found 8 hours ago
LATAM Airlines Group
Mon, Aug 25 - Sun, Aug 31
JFK
New York
VVI
Santa Cruz
$1,260 Roundtrip, found 8 hours ago
$1,260
Roundtrip
found 8 hours ago
Select LATAM Airlines Group flight, departing Mon, Aug 25 from New York to Santa Cruz, returning Sun, Aug 31, priced at $1,260 found 8 hours ago
GOL Linhas Aereas S.A.
Mon, Aug 25 - Sun, Aug 31
JFK
New York
VVI
Santa Cruz
$2,557 Roundtrip, found 8 hours ago
$2,557
Roundtrip
found 8 hours ago
Select GOL Linhas Aereas S.A. flight, departing Mon, Aug 25 from New York to Santa Cruz, returning Sun, Aug 31, priced at $2,557 found 8 hours ago