San Antonio Vacation Packages for 2026

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Top Hotel Deals

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
1.38 km from San Antonio
Book a stay at this business-friendly hotel in San Miguelito. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
12.43 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
12.8 km from San Antonio
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
6.06 km from San Antonio
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
10.39 km from San Antonio
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
12.82 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
12.74 km from San Antonio
Book a stay at this spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Avenida Balboa are ...
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
13.12 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
12.82 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
12.22 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
23.79 km from San Antonio
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
23.39 km from San Antonio
Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Hotel Ojos del Rio

Hotel Ojos del Rio

3.5 out of 5
calle 41 este Panama City Panama
13.91 km from San Antonio
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
15.78 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
12.37 km from San Antonio
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Mar 11 - Wed, Mar 18
MIA
Miami Intl.
PTY
Tocumen Intl.
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select Copa flight, departing Wed, Mar 11 from Miami Intl. to Tocumen Intl., returning Wed, Mar 18, priced at $318 found 6 days ago
American Airlines
Fri, May 15 - Fri, Jun 5
MIA
Miami Intl.
PTY
Tocumen Intl.
$331 Roundtrip, found 2 hours ago
$331
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, May 15 from Miami Intl. to Tocumen Intl., returning Fri, Jun 5, priced at $331 found 2 hours ago
United
Wed, Mar 11 - Wed, Mar 18
MIA
Miami Intl.
PTY
Tocumen Intl.
$333 Roundtrip, found 6 days ago
$333
Roundtrip
found 6 days ago
Select United flight, departing Wed, Mar 11 from Miami Intl. to Tocumen Intl., returning Wed, Mar 18, priced at $333 found 6 days ago
avianca
Mon, Oct 26 - Sun, Nov 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$360 Roundtrip, found 1 day ago
$360
Roundtrip
found 1 day ago
Select avianca flight, departing Mon, Oct 26 from Miami Intl. to Tocumen Intl., returning Sun, Nov 1, priced at $360 found 1 day ago
Delta
Sun, Apr 12 - Thu, Apr 30
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$500 Roundtrip, found 1 day ago
$500
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Apr 12 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Thu, Apr 30, priced at $500 found 1 day ago