
San Antonio Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
San Antonio Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Las Americas Golden Tower Panama
San Francisco
Price was $929, price is now $732 per person
$732
per person
Mar 19 - Mar 23
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Megapolis Hotel Panamá
San Francisco
Price was $1,361, price is now $1,000 per person
$1,000
per person
Mar 19 - Mar 23
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Hotel Riu Plaza Panama
Bella Vista
Price was $984, price is now $734 per person
$734
per person
Mar 19 - Mar 23
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Riande Aeropuerto Hotel & Casino
Price was $972, price is now $764 per person
$764
per person
Mar 19 - Mar 23
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Waldorf Astoria Panama
Bella Vista
Price was $1,099, price is now $897 per person
$897
per person
Mar 19 - Mar 23
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
12.43 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
6.06 km from San Antonio
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...

Megapolis Hotel Panamá
Avenida Balboa Panama City
12.53 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
13.12 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
12.71 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
12.37 km from San Antonio
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
15.78 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...

Principe Hotel and Suites
Via Argentina Panama City Panama
12.22 km from San Antonio
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...

The Westin Playa Bonita Panama
Km 6 Road to Veracruz Veracruz Panama
23.39 km from San Antonio
Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
11.98 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
12.8 km from San Antonio
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
23.79 km from San Antonio
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...

Hyatt Regency Panama City
Calle 52 and Ricardo Arias Panama City
12.78 km from San Antonio
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Mar 29 - Mon, Apr 13
MIA
Miami Intl.
PTY
Tocumen Intl.
$365 Roundtrip, found 5 hours ago
$365
Roundtrip
found 5 hours ago

Wed, Jan 28 - Sat, Feb 28
MIA
Miami Intl.
PTY
Tocumen Intl.
$366 Roundtrip, found 13 hours ago
$366
Roundtrip
found 13 hours ago

Mon, Feb 2 - Mon, Mar 2
MIA
Miami Intl.
PTY
Tocumen Intl.
$390 Roundtrip, found 13 hours ago
$390
Roundtrip
found 13 hours ago

Mon, Feb 23 - Wed, Mar 11
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$429 Roundtrip, found 5 days ago
$429
Roundtrip
found 5 days ago

Mon, Feb 2 - Mon, Mar 2
MIA
Miami Intl.
PTY
Tocumen Intl.
$721 Roundtrip, found 13 hours ago
$721
Roundtrip
found 13 hours ago

