
Otay Mesa West Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Otay Mesa West Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Price was $834, price is now $608 per person
$608
per person
Jun 9 - Jun 13
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this spa hotel in Escondido. Enjoy free parking, 8 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in our reviews. Popular attractions The Oaks Course and Cal-a-vie are located nearby.

The Sofia Hotel
Downtown San Diego
Save 100% on your flight
Price was $1,128, price is now $675 per person
$675
per person
Jun 9 - Jun 13
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

The DEXTRO Little Italy, BW Premier Collection
Downtown San Diego
Save 100% on your flight
Price was $954, price is now $649 per person
$649
per person
Jun 9 - Jun 13
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

Rancho Bernardo Inn
Rancho Bernardo
Save 100% on your flight
Price was $1,267, price is now $947 per person
$947
per person
Jun 1 - Jun 5
found 12 hours ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this luxury resort in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Rancho Bernardo Inn Course and Oaks North Golf Club are located nearby.

Ancora by Avantstay Multi-room Reservation Luxury Resort Pool + Sky Deck Walkable Little Italy
Downtown San Diego
Save 100% on your flight
Price was $3,416, price is now $2,557 per person
$2,557
per person
Jun 15 - Jun 19
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Stay at this apartment in San Diego. Enjoy in-room washers/dryers, air conditioning, and an outdoor pool. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

The Beau Hotel Gaslamp Quarter San Diego
Downtown San Diego
Price was $1,111, price is now $836 per person
$836
per person
Jun 15 - Jun 19
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.
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Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
27.94 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
17.51 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
19.06 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

The Sofia Hotel
150 W Broadway San Diego CA
18.5 km from Otay Mesa West
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
18.19 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
19.21 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

Handlery Hotel
950 Hotel Cir N San Diego CA
23.14 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
21.38 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...

Best Western Seven Seas
411 Hotel Circle South San Diego CA
22.89 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
22.12 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...

California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
30.62 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
23.94 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
27.13 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, May 30 - Tue, Jun 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$87 Roundtrip, found 3 days ago
$87
Roundtrip
found 3 days ago

Tue, Sep 15 - Tue, Sep 22
PDX
Portland Intl.
SAN
San Diego Intl.
$165 Roundtrip, found 9 hours ago
$165
Roundtrip
found 9 hours ago

Wed, Jun 3 - Mon, Jun 8
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$179 Roundtrip, found 7 hours ago
$179
Roundtrip
found 7 hours ago

Tue, May 26 - Sat, May 30
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago

Tue, Jun 2 - Tue, Jun 16
PAE
Seattle Paine Field Intl. Airport
SAN
San Diego Intl.
$274 Roundtrip, found 7 hours ago
$274
Roundtrip
found 7 hours ago

