Otay Mesa West Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Otay Mesa West Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Fairfield Inn & Suites San Diego Old Town
Old Town San Diego
Save 100% on your flight
Price was $575, price is now $389 per person
$389
per person
Apr 14 - Apr 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Port of San Diego and San Diego Zoo are located nearby.
The Sofia Hotel
Downtown San Diego
Price was $1,229, price is now $616 per person
$616
per person
Apr 14 - Apr 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Los Bungalows
Save 100% on your flight
Price was $833, price is now $482 per person
$482
per person
May 1 - May 6
found 7 hours ago
Roundtrip flight included
Seattle (SEA) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions Las Americas Premium Outlets and Imperial Beach are located nearby.
Coronado Beach Resort
Glorietta Bay
Save 100% on your flight
Price was $785, price is now $515 per person
$515
per person
Apr 14 - Apr 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this condo in Coronado. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
The Beau Downtown San Diego Gaslamp Quar
Downtown San Diego
Save 100% on your flight
Price was $804, price is now $529 per person
$529
per person
Apr 14 - Apr 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.
Kona Kai San Diego
Point Loma
Save 100% on your flight
Price was $1,161, price is now $775 per person
$775
per person
Apr 14 - Apr 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
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Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
27.94 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Best Western Seven Seas
411 Hotel Circle South San Diego CA
22.89 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
17.51 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
19.06 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
22.93 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Handlery Hotel
950 Hotel Cir N San Diego CA
23.14 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
The Sofia Hotel
150 W Broadway San Diego CA
18.5 km from Otay Mesa West
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
18.19 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
19.21 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
27.13 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
26.81 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
22.12 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
3888 Greenwood St San Diego CA
24.32 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mon, Apr 6 - Mon, Apr 13
DEN
Denver Intl.
SAN
San Diego Intl.
$66 Roundtrip, found 1 day ago
$66
Roundtrip
found 1 day ago
Tue, Apr 14 - Tue, Apr 28
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$99 Roundtrip, found 4 days ago
$99
Roundtrip
found 4 days ago
Tue, May 5 - Fri, May 8
PDX
Portland Intl.
SAN
San Diego Intl.
$148 Roundtrip, found 7 hours ago
$148
Roundtrip
found 7 hours ago
Mon, Apr 6 - Mon, Apr 13
DEN
Denver Intl.
CLD
McClellan-Palomar
$159 Roundtrip, found 1 day ago
$159
Roundtrip
found 1 day ago
Tue, Apr 14 - Wed, Apr 29
JFK
John F. Kennedy Intl.
SAN
San Diego Intl.
$237 Roundtrip, found 5 days ago
$237
Roundtrip
found 5 days ago