Mission Bay Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Mission Bay Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel
Downtown San Diego
Price was $969, price is now $434 per person
$434
per person
Jul 26 - Jul 30
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Ocean Park Inn
Pacific Beach
Save 100% on your flight
Price was $2,908, price is now $1,789 per person
$1,789
per person
Aug 19 - Aug 26
found 23 hours ago
Roundtrip flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this beach hotel in San Diego. Enjoy free breakfast, free WiFi, and a beach locale. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Paradise Point Resort & Spa
Mission Bay
Save 100% on your flight
Price was $1,758, price is now $1,101 per person
$1,101
per person
Sep 9 - Sep 16
found 18 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
Urban Boutique Hotel
Downtown San Diego
Save 100% on your flight
Price was $1,209, price is now $763 per person
$763
per person
Sep 9 - Sep 16
found 18 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
Price was $1,210, price is now $784 per person
$784
per person
Sep 9 - Sep 16
found 2 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this spa hotel in Escondido. Enjoy free parking, 8 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in our reviews. Popular attractions The Oaks Course and Cal-a-vie are located nearby.
Embassy Suites by Hilton San Diego La Jolla
University City
Save 100% on your flight
Price was $1,449, price is now $984 per person
$984
per person
Sep 9 - Sep 16
found 18 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, 2 restaurants, and a free beach shuttle. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions La Jolla Cove and Torrey Pines Golf Course are located nearby.
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San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
1.16 km from Mission Bay
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
1.55 km from Mission Bay
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
1.75 km from Mission Bay
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd San Diego CA
2.01 km from Mission Bay
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
8.97 km from Mission Bay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
The Sofia Hotel
150 W Broadway San Diego CA
8.69 km from Mission Bay
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
7.95 km from Mission Bay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Best Western Seven Seas
411 Hotel Circle South San Diego CA
5.61 km from Mission Bay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
9.66 km from Mission Bay
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
7.79 km from Mission Bay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
Bahia Resort Hotel
998 W Mission Bay Dr San Diego CA
2.28 km from Mission Bay
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
5.48 km from Mission Bay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
11.45 km from Mission Bay
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Tue, Jul 21 - Tue, Jul 28
SFO
San Francisco Intl.
SAN
San Diego Intl.
$66 Roundtrip, found 22 hours ago
$66
Roundtrip
found 22 hours ago
Tue, Nov 3 - Tue, Dec 1
PDX
Portland Intl.
SAN
San Diego Intl.
$145 Roundtrip, found 23 hours ago
$145
Roundtrip
found 23 hours ago
Tue, Aug 25 - Tue, Sep 8
BOS
Logan Intl.
SAN
San Diego Intl.
$252 Roundtrip, found 3 days ago
$252
Roundtrip
found 3 days ago
Sun, Dec 6 - Sun, Dec 13
MSP
Minneapolis - St. Paul Intl.
SAN
San Diego Intl.
$267 Roundtrip, found 5 days ago
$267
Roundtrip
found 5 days ago
Tue, Jul 21 - Tue, Jul 28
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$269 Roundtrip, found 22 hours ago
$269
Roundtrip
found 22 hours ago