Great Lakes Seaway Vacation Packages for 2025

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Great Lakes Seaway Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Cleveland/Independence

Hampton Inn & Suites Cleveland/Independence

2.5 out of 5
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Book a stay at this business-friendly hotel in Independence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cleveland Metroparks Zoo and Topgolf are located nearby.

The Westin Cleveland Downtown

The Westin Cleveland Downtown

4 out of 5
Downtown Cleveland
Save 100% on your flight
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Rock and Roll Hall of Fame and Huntington Bank Field are located nearby.

InterContinental Suites Hotel Cleveland by IHG

InterContinental Suites Hotel Cleveland by IHG

4 out of 5
Fairfax
Save 100% on your flight
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Stay at this 4-star business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions Progressive Field and Rock and Roll Hall of Fame are located nearby.

Wyndham Avon

Wyndham Avon

3.5 out of 5
Save 100% on your flight
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Stay at this 3.5-star business-friendly hotel in Avon. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Miller Nature Preserve and Klingshirn Winery are located nearby.

DoubleTree by Hilton Hotel Cleveland Downtown - Lakeside

DoubleTree by Hilton Hotel Cleveland Downtown - Lakeside

4 out of 5
Downtown Cleveland
Save 100% on your flight
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Stay at this 4-star business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Rock and Roll Hall of Fame and Huntington Bank Field are located nearby.

The Orbit Hotel, Trademark Collection by Wyndham

The Orbit Hotel, Trademark Collection by Wyndham

2.5 out of 5
per person
Sep 24 - Sep 29
found 15 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Cleveland (CLE)
Book a stay at this business-friendly hotel in Fairview Park. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Rocky River Reservation and Rocky River are located nearby.

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Top Hotel Deals

Wyndham Garden at Niagara Falls

Wyndham Garden at Niagara Falls

3 out of 5
443 Main St, Niagara Falls, NY
78.38 km from city center
Stay at this 3-star business-friendly hotel in Niagara Falls. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
Seneca Niagara Resort & Casino

Seneca Niagara Resort & Casino

4 out of 5
310 4th St, Niagara Falls, NY
78.22 km from city center
Stay at this 4-star spa hotel in Niagara Falls. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
83.82 km from city center
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the bar ...
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
79.21 km from city center
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff ...
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
70.54 km from city center
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Fairbridge Inn Express Buffalo Airport Williamsville

Fairbridge Inn Express Buffalo Airport Williamsville

2 out of 5
7200 Transit Road, Buffalo, NY
87 km from city center
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Walden Galleria Mall and Eastern Hills Mall are located ...
Sheraton Niagara Falls

Sheraton Niagara Falls

4 out of 5
300 3rd St, Niagara Falls, NY
78.23 km from city center
Stay at this 4-star business-friendly hotel in Niagara Falls. Enjoy 2 hot tubs, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Cambria Hotel Niagara Falls

Cambria Hotel Niagara Falls

3 out of 5
311 Rainbow Blvd, Niagara Falls, NY
77.95 km from city center
Stay at this 3-star family-friendly hotel in Niagara Falls. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Comfort Inn The Pointe

Comfort Inn The Pointe

3 out of 5
1 Prospect Pointe, Niagara Falls, NY
78.13 km from city center
Book a stay at this business-friendly hotel in Niagara Falls. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the ...
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3 out of 5
145 Innkeepers Lane, Buffalo, NY
82.78 km from city center
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Erie by IHG

Holiday Inn Erie by IHG

3 out of 5
2260 DOWNS DRIVE, Erie, PA
66.01 km from city center
Stay at this 3-star hotel in Erie. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms ...
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road, Grand Island, NY
77.67 km from city center
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Extended Stay America Suites - Buffalo - Airport

Extended Stay America Suites - Buffalo - Airport

2.5 out of 5
901 Dick Rd, Buffalo, NY
81.65 km from city center
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Walden Galleria Mall and Buffalo ...
Comfort Inn University

Comfort Inn University

2.5 out of 5
1 Flint Rd, Buffalo, NY
83.16 km from city center
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Days Inn by Wyndham Erie

Days Inn by Wyndham Erie

2 out of 5
6101 Wattsburg Rd, Erie, PA
57.67 km from city center
Book a stay at this business-friendly hotel in Erie. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Sep 3 - Wed, Sep 10
JFK
John F. Kennedy Intl.
BUF
Buffalo Niagara Intl.
$137 Roundtrip, found 5 days ago
$137
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Sep 3 from John F. Kennedy Intl. to Buffalo Niagara Intl., returning Wed, Sep 10, priced at $137 found 5 days ago
Delta
Wed, Sep 3 - Sat, Sep 6
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$137 Roundtrip, found 5 days ago
$137
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Sep 3 from LaGuardia to Buffalo Niagara Intl., returning Sat, Sep 6, priced at $137 found 5 days ago
Frontier Airlines
Sun, Oct 5 - Mon, Oct 6
ATL
Hartsfield-Jackson Atlanta Intl.
BUF
Buffalo Niagara Intl.
$138 Roundtrip, found 5 days ago
$138
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Oct 5 from Hartsfield-Jackson Atlanta Intl. to Buffalo Niagara Intl., returning Mon, Oct 6, priced at $138 found 5 days ago
American Airlines
Tue, Jul 29 - Wed, Jul 30
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$157 Roundtrip, found 4 days ago
$157
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jul 29 from LaGuardia to Buffalo Niagara Intl., returning Wed, Jul 30, priced at $157 found 4 days ago
United
Sun, Aug 31 - Sat, Sep 6
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$187 Roundtrip, found 5 days ago
$187
Roundtrip
found 5 days ago
Select United flight, departing Sun, Aug 31 from LaGuardia to Buffalo Niagara Intl., returning Sat, Sep 6, priced at $187 found 5 days ago